Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1S All Species: 12.73
Human Site: Y973 Identified Species: 40
UniProt: Q13698 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13698 NP_000060.2 1873 212350 Y973 E E C R G Y Y Y V Y K D G D P
Chimpanzee Pan troglodytes XP_525018 1874 212521 Y974 P C H R G Y Y Y V Y K D G D P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848685 1876 212961 Y976 Q E C R G Y Y Y V Y K D G D P
Cat Felis silvestris
Mouse Mus musculus Q02789 1880 213241 Y973 E E C R G Y Y Y I Y K D G D P
Rat Rattus norvegicus P22002 2169 243464 I1103 A E S K G N Y I T Y K T G E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 I1081 E E C R G I Y I V Y K D G D V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139622 1777 202411 M953 V T M L L D F M F A C I G V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24270 2516 276682 L1518 D E C Y G T Y L V Y D D G D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 91.5 N.A. 90.9 58 N.A. N.A. 56.8 N.A. 67.8 N.A. 40.5 N.A. N.A. N.A.
Protein Similarity: 100 98.8 N.A. 94.9 N.A. 94.7 69.6 N.A. N.A. 68.5 N.A. 78.9 N.A. 52.5 N.A. N.A. N.A.
P-Site Identity: 100 80 N.A. 93.3 N.A. 93.3 40 N.A. N.A. 80 N.A. 6.6 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 80 N.A. 100 N.A. 100 53.3 N.A. N.A. 80 N.A. 13.3 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % A
% Cys: 0 13 63 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 13 0 0 0 0 13 0 0 0 0 13 75 0 75 0 % D
% Glu: 38 75 0 0 0 0 0 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 13 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 88 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 25 13 0 0 13 0 0 0 % I
% Lys: 0 0 0 13 0 0 0 0 0 0 75 0 0 0 0 % K
% Leu: 0 0 0 13 13 0 0 13 0 0 0 0 0 0 0 % L
% Met: 0 0 13 0 0 0 0 13 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % P
% Gln: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % Q
% Arg: 0 0 0 63 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 13 0 0 0 13 0 0 13 0 0 13 0 0 0 % T
% Val: 13 0 0 0 0 0 0 0 63 0 0 0 0 13 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 50 88 50 0 88 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _