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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR2B
All Species:
16.36
Human Site:
S182
Identified Species:
30
UniProt:
Q13705
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13705
NP_001097.2
512
57724
S182
D
P
G
P
P
P
P
S
P
L
V
G
L
K
P
Chimpanzee
Pan troglodytes
XP_001171684
516
58074
P182
A
L
P
Q
D
P
G
P
P
P
P
S
P
L
V
Rhesus Macaque
Macaca mulatta
XP_001084713
521
58857
S191
D
P
G
P
P
P
P
S
P
L
V
G
L
K
P
Dog
Lupus familis
XP_542709
507
57202
A202
R
F
G
C
V
W
K
A
Q
L
M
N
D
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P27040
536
60524
A182
V
R
Q
C
Q
R
W
A
G
R
R
D
G
C
A
Rat
Rattus norvegicus
P38445
513
57839
S182
D
P
G
P
P
P
P
S
P
L
V
G
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518896
634
71047
P332
V
H
G
D
P
G
P
P
P
P
S
P
L
L
G
Chicken
Gallus gallus
Q90670
512
57758
S182
D
P
G
P
P
P
P
S
P
L
V
G
L
K
P
Frog
Xenopus laevis
P27041
511
57917
V184
L
P
P
P
S
P
L
V
G
L
K
P
L
Q
L
Zebra Danio
Brachydanio rerio
NP_571285
509
57460
L182
G
P
S
P
P
S
P
L
V
G
L
K
P
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395928
531
60411
S198
P
L
P
L
P
Q
P
S
P
N
L
G
L
R
P
Nematode Worm
Caenorhab. elegans
P50488
744
84391
K269
E
E
I
K
K
Q
Q
K
I
K
F
D
M
E
K
Sea Urchin
Strong. purpuratus
XP_001194466
553
62367
N198
E
P
T
P
S
P
M
N
S
L
P
P
I
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
95.9
97
N.A.
94.9
98.8
N.A.
41.6
89.4
82.8
79.3
N.A.
N.A.
51.4
25.8
49.7
Protein Similarity:
100
98.6
95.9
97.6
N.A.
94.9
99
N.A.
54.7
95.6
92.7
90
N.A.
N.A.
68.3
39.5
64
P-Site Identity:
100
13.3
100
13.3
N.A.
0
100
N.A.
33.3
100
33.3
26.6
N.A.
N.A.
46.6
0
26.6
P-Site Similarity:
100
13.3
100
26.6
N.A.
6.6
100
N.A.
33.3
100
40
33.3
N.A.
N.A.
60
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
31
0
0
8
8
0
0
0
0
0
0
16
8
0
0
% D
% Glu:
16
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
0
47
0
0
8
8
0
16
8
0
39
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
8
0
8
8
0
8
8
8
0
31
8
% K
% Leu:
8
16
0
8
0
0
8
8
0
54
16
0
54
24
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% N
% Pro:
8
54
24
54
54
54
54
16
54
16
16
24
16
0
39
% P
% Gln:
0
0
8
8
8
16
8
0
8
0
0
0
0
16
8
% Q
% Arg:
8
8
0
0
0
8
0
0
0
8
8
0
0
8
0
% R
% Ser:
0
0
8
0
16
8
0
39
8
0
8
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
16
0
0
0
8
0
0
8
8
0
31
0
0
0
16
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _