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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 10.91
Human Site: S279 Identified Species: 17.14
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 S279 L L T E M V K S R L N S W F Q
Chimpanzee Pan troglodytes XP_001159538 837 91907 S279 L L T E M V K S R L N S W F Q
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 S279 L L T E M V K S R L N S W F Q
Dog Lupus familis XP_540220 836 92340 L278 T E M V K S R L N S W F Q H R
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 V276 L P Q L T D M V K S R L N S W
Rat Rattus norvegicus O88941 834 91853 V276 L P L L T D M V K S H L N S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 L263 T D V V R T S L R D H F T H P
Zebra Danio Brachydanio rerio NP_001073659 841 96206 V274 L D K L T D I V K N S L N H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 K279 A P S L A K L K D T L F S H F
Honey Bee Apis mellifera XP_395198 782 90486 K260 P L S A D G K K K D A N F I A
Nematode Worm Caenorhab. elegans Q19426 796 92627 N271 N A P N Q P L N Y I L N E K H
Sea Urchin Strong. purpuratus NP_001157279 829 93116 T295 L V G N D Q Q T I E A S P D K
Poplar Tree Populus trichocarpa XP_002315613 845 96641 E299 N L G A Q A R E F G Q L L L S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 K297 N L A L Q A R K F G R L Q L S
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 N309 F Q F D I T Y N K L G T T Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 0 N.A. 6.6 6.6 N.A. N.A. N.A. 6.6 6.6 N.A. 0 13.3 0 13.3
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 20 N.A. N.A. N.A. 13.3 26.6 N.A. 6.6 40 20 40
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 14 7 14 0 0 0 0 14 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 14 20 0 0 7 14 0 0 0 7 0 % D
% Glu: 0 7 0 20 0 0 0 7 0 7 0 0 7 0 0 % E
% Phe: 7 0 7 0 0 0 0 0 14 0 0 20 7 20 7 % F
% Gly: 0 0 14 0 0 7 0 0 0 14 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 14 0 0 27 7 % H
% Ile: 0 0 0 0 7 0 7 0 7 7 0 0 0 7 0 % I
% Lys: 0 0 7 0 7 7 27 20 34 0 0 0 0 7 14 % K
% Leu: 47 40 7 34 0 0 14 14 0 27 14 34 7 14 0 % L
% Met: 0 0 7 0 20 0 14 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 14 0 0 0 14 7 7 20 14 20 0 0 % N
% Pro: 7 20 7 0 0 7 0 0 0 0 0 0 7 0 7 % P
% Gln: 0 7 7 0 20 7 7 0 0 0 7 0 14 7 20 % Q
% Arg: 0 0 0 0 7 0 20 0 27 0 14 0 0 0 7 % R
% Ser: 0 0 14 0 0 7 7 20 0 20 7 27 7 14 20 % S
% Thr: 14 0 20 0 20 14 0 7 0 7 0 7 14 0 0 % T
% Val: 0 7 7 14 0 20 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 20 0 14 % W
% Tyr: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _