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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 22.12
Human Site: S440 Identified Species: 34.76
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 S440 P L F T A V P S R S F F P R G
Chimpanzee Pan troglodytes XP_001159538 837 91907 S440 P L F T A V P S R S F F P R G
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 S440 P L F T A V P S R S F F P R G
Dog Lupus familis XP_540220 836 92340 S439 P L F T A V P S R S F F P R G
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 S437 P L F S G V P S R S F F P R G
Rat Rattus norvegicus O88941 834 91853 S437 P L F S G V P S R S F F P R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 R423 P S R S F F P R G F L W D E G
Zebra Danio Brachydanio rerio NP_001073659 841 96206 R434 P S R S F F P R G F L W D E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 R439 P S R S F F P R G F L W D E G
Honey Bee Apis mellifera XP_395198 782 90486 R421 N I E G W I P R E M I L G Q E
Nematode Worm Caenorhab. elegans Q19426 796 92627 A443 E M I V G S E A E A K V P A E
Sea Urchin Strong. purpuratus NP_001157279 829 93116 A456 H W L D L M N A D G W I P R E
Poplar Tree Populus trichocarpa XP_002315613 845 96641 H459 L I W R W D I H I C L D I I G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 R459 L I W R W D I R I T L D I V G
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 A469 E I I L G N E A R S K V P Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 20 20 N.A. 20 6.6 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 33.3 33.3 N.A. 33.3 26.6 26.6 33.3
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 20 N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 27 0 0 20 0 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 14 0 0 7 0 0 14 20 0 0 % D
% Glu: 14 0 7 0 0 0 14 0 14 0 0 0 0 20 27 % E
% Phe: 0 0 40 0 20 20 0 0 0 20 40 40 0 0 0 % F
% Gly: 0 0 0 7 27 0 0 0 20 7 0 0 7 0 74 % G
% His: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 27 14 0 0 7 14 0 14 0 7 7 14 7 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % K
% Leu: 14 40 7 7 7 0 0 0 0 0 34 7 0 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % N
% Pro: 60 0 0 0 0 0 67 0 0 0 0 0 60 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % Q
% Arg: 0 0 20 14 0 0 0 34 47 0 0 0 0 47 0 % R
% Ser: 0 20 0 34 0 7 0 40 0 47 0 0 0 0 0 % S
% Thr: 0 0 0 27 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 7 0 40 0 0 0 0 0 14 0 7 0 % V
% Trp: 0 7 14 0 20 0 0 0 0 0 7 20 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _