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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 9.09
Human Site: S465 Identified Species: 14.29
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 S465 V V Q R W D P S L T R E A L G
Chimpanzee Pan troglodytes XP_001159538 837 91907 S465 V V Q R W D P S L T R E A L G
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 S465 V V Q R W D P S L T R E A L G
Dog Lupus familis XP_540220 836 92340 R464 V V Q R W D P R L T R E V L G
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 H462 V V Q R W D P H L T R E A L G
Rat Rattus norvegicus O88941 834 91853 H462 V V Q R W D P H L T R E A L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 A442 L I A R W S P A L A W Q S L V
Zebra Danio Brachydanio rerio NP_001073659 841 96206 Q453 L L S K W D T Q L T Q E V F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 D458 L I S A W D I D I E L D I I C
Honey Bee Apis mellifera XP_395198 782 90486 Q440 V P E E F V T Q I N T N A N P
Nematode Worm Caenorhab. elegans Q19426 796 92627 F465 V A N P P T L F Y V M D K L V
Sea Urchin Strong. purpuratus NP_001157279 829 93116 K473 L D S E A R S K V P A E F V V
Poplar Tree Populus trichocarpa XP_002315613 845 96641 W477 D L M N I D G W I P R E Q I L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 W477 D L L N I D G W I P R E Q I L
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 M497 L L L A F S E M L S R A I E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. N.A. 33.3 33.3 N.A. 13.3 13.3 13.3 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. N.A. 66.6 60 N.A. 46.6 33.3 20 26.6
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 20 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 14 7 0 0 7 0 7 7 7 40 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 14 7 0 0 0 67 0 7 0 0 0 14 0 0 0 % D
% Glu: 0 0 7 14 0 0 7 0 0 7 0 67 0 7 0 % E
% Phe: 0 0 0 0 14 0 0 7 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 40 % G
% His: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % H
% Ile: 0 14 0 0 14 0 7 0 27 0 0 0 14 20 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 0 0 7 0 0 % K
% Leu: 34 27 14 0 0 0 7 0 60 0 7 0 0 54 14 % L
% Met: 0 0 7 0 0 0 0 7 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 14 0 0 0 0 0 7 0 7 0 7 7 % N
% Pro: 0 7 0 7 7 0 47 0 0 20 0 0 0 0 7 % P
% Gln: 0 0 40 0 0 0 0 14 0 0 7 7 14 0 0 % Q
% Arg: 0 0 0 47 0 7 0 7 0 0 60 0 0 0 0 % R
% Ser: 0 0 20 0 0 14 7 20 0 7 0 0 7 0 0 % S
% Thr: 0 0 0 0 0 7 14 0 0 47 7 0 0 0 0 % T
% Val: 54 40 0 0 0 7 0 0 7 7 0 0 14 7 20 % V
% Trp: 0 0 0 0 60 0 0 14 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _