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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 10.61
Human Site: T274 Identified Species: 16.67
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 T274 N P G L P L L T E M V K S R L
Chimpanzee Pan troglodytes XP_001159538 837 91907 T274 N P G L P L L T E M V K S R L
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 T274 N P G L P L L T E M V K S R L
Dog Lupus familis XP_540220 836 92340 M273 G L P L L T E M V K S R L N S
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 Q271 S S N P G L P Q L T D M V K S
Rat Rattus norvegicus O88941 834 91853 L271 S S N P G L P L L T D M V K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 V258 G L H T V T D V V R T S L R D
Zebra Danio Brachydanio rerio NP_001073659 841 96206 K269 T R S P G L D K L T D I V K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 S274 Y L S T V A P S L A K L K D T
Honey Bee Apis mellifera XP_395198 782 90486 S255 A G E Q I P L S A D G K K K D
Nematode Worm Caenorhab. elegans Q19426 796 92627 P266 N T Q A Y N A P N Q P L N Y I
Sea Urchin Strong. purpuratus NP_001157279 829 93116 G290 T Q L L G L V G N D Q Q T I E
Poplar Tree Populus trichocarpa XP_002315613 845 96641 G294 D L V Q H N L G A Q A R E F G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 A292 D L V Q Q N L A L Q A R K F G
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 F304 T K K D G F Q F D I T Y N K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. 6.6 6.6 N.A. 0 13.3 6.6 13.3
P-Site Similarity: 100 100 100 13.3 N.A. 20 20 N.A. N.A. N.A. 6.6 13.3 N.A. 6.6 26.6 20 33.3
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 7 7 7 14 7 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 7 0 0 14 0 7 14 20 0 0 7 14 % D
% Glu: 0 0 7 0 0 0 7 0 20 0 0 0 7 0 7 % E
% Phe: 0 0 0 0 0 7 0 7 0 0 0 0 0 14 0 % F
% Gly: 14 7 20 0 34 0 0 14 0 0 7 0 0 0 14 % G
% His: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 7 0 7 0 7 7 % I
% Lys: 0 7 7 0 0 0 0 7 0 7 7 27 20 34 0 % K
% Leu: 0 34 7 34 7 47 40 7 34 0 0 14 14 0 27 % L
% Met: 0 0 0 0 0 0 0 7 0 20 0 14 0 0 0 % M
% Asn: 27 0 14 0 0 20 0 0 14 0 0 0 14 7 7 % N
% Pro: 0 20 7 20 20 7 20 7 0 0 7 0 0 0 0 % P
% Gln: 0 7 7 20 7 0 7 7 0 20 7 7 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 7 0 20 0 27 0 % R
% Ser: 14 14 14 0 0 0 0 14 0 0 7 7 20 0 20 % S
% Thr: 20 7 0 14 0 14 0 20 0 20 14 0 7 0 7 % T
% Val: 0 0 14 0 14 0 7 7 14 0 20 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 0 0 0 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _