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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOGS
All Species:
10.61
Human Site:
T274
Identified Species:
16.67
UniProt:
Q13724
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13724
NP_001139630.1
837
91918
T274
N
P
G
L
P
L
L
T
E
M
V
K
S
R
L
Chimpanzee
Pan troglodytes
XP_001159538
837
91907
T274
N
P
G
L
P
L
L
T
E
M
V
K
S
R
L
Rhesus Macaque
Macaca mulatta
XP_001109499
837
92099
T274
N
P
G
L
P
L
L
T
E
M
V
K
S
R
L
Dog
Lupus familis
XP_540220
836
92340
M273
G
L
P
L
L
T
E
M
V
K
S
R
L
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80UM7
834
91813
Q271
S
S
N
P
G
L
P
Q
L
T
D
M
V
K
S
Rat
Rattus norvegicus
O88941
834
91853
L271
S
S
N
P
G
L
P
L
L
T
D
M
V
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121329
826
93558
V258
G
L
H
T
V
T
D
V
V
R
T
S
L
R
D
Zebra Danio
Brachydanio rerio
NP_001073659
841
96206
K269
T
R
S
P
G
L
D
K
L
T
D
I
V
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572707
849
96131
S274
Y
L
S
T
V
A
P
S
L
A
K
L
K
D
T
Honey Bee
Apis mellifera
XP_395198
782
90486
S255
A
G
E
Q
I
P
L
S
A
D
G
K
K
K
D
Nematode Worm
Caenorhab. elegans
Q19426
796
92627
P266
N
T
Q
A
Y
N
A
P
N
Q
P
L
N
Y
I
Sea Urchin
Strong. purpuratus
NP_001157279
829
93116
G290
T
Q
L
L
G
L
V
G
N
D
Q
Q
T
I
E
Poplar Tree
Populus trichocarpa
XP_002315613
845
96641
G294
D
L
V
Q
H
N
L
G
A
Q
A
R
E
F
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176916
852
97616
A292
D
L
V
Q
Q
N
L
A
L
Q
A
R
K
F
G
Baker's Yeast
Sacchar. cerevisiae
P53008
833
96488
F304
T
K
K
D
G
F
Q
F
D
I
T
Y
N
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
89.7
N.A.
86.5
85.1
N.A.
N.A.
N.A.
49.7
48.1
N.A.
41.7
38.1
36.4
46
Protein Similarity:
100
99.5
98
93
N.A.
90.8
90.4
N.A.
N.A.
N.A.
65.2
63.9
N.A.
55.3
54.9
51.6
62.2
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
0
13.3
6.6
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
20
20
N.A.
N.A.
N.A.
6.6
13.3
N.A.
6.6
26.6
20
33.3
Percent
Protein Identity:
40.1
N.A.
N.A.
38.7
23.6
N.A.
Protein Similarity:
57.1
N.A.
N.A.
55.2
41.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
7
7
7
14
7
14
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
7
0
0
14
0
7
14
20
0
0
7
14
% D
% Glu:
0
0
7
0
0
0
7
0
20
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
0
0
0
14
0
% F
% Gly:
14
7
20
0
34
0
0
14
0
0
7
0
0
0
14
% G
% His:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
7
0
7
0
7
7
% I
% Lys:
0
7
7
0
0
0
0
7
0
7
7
27
20
34
0
% K
% Leu:
0
34
7
34
7
47
40
7
34
0
0
14
14
0
27
% L
% Met:
0
0
0
0
0
0
0
7
0
20
0
14
0
0
0
% M
% Asn:
27
0
14
0
0
20
0
0
14
0
0
0
14
7
7
% N
% Pro:
0
20
7
20
20
7
20
7
0
0
7
0
0
0
0
% P
% Gln:
0
7
7
20
7
0
7
7
0
20
7
7
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
7
0
20
0
27
0
% R
% Ser:
14
14
14
0
0
0
0
14
0
0
7
7
20
0
20
% S
% Thr:
20
7
0
14
0
14
0
20
0
20
14
0
7
0
7
% T
% Val:
0
0
14
0
14
0
7
7
14
0
20
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _