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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 12.42
Human Site: Y260 Identified Species: 19.52
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 Y260 T A P K Y G S Y N V F W T S N
Chimpanzee Pan troglodytes XP_001159538 837 91907 Y260 T A P K Y G S Y N V F W T S N
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 Y260 T A P K Y G S Y N V F W T S N
Dog Lupus familis XP_540220 836 92340 V259 P K Y S S Y N V F W S S N P G
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 G257 G D T V P K H G S Y N V F W S
Rat Rattus norvegicus O88941 834 91853 G257 G D T V P K H G S Y N V F W S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 Y244 G S H I S Y N Y L S T S C P G
Zebra Danio Brachydanio rerio NP_001073659 841 96206 A255 E G A S A K Y A R Y N F L Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 G260 V R F H A V K G K I L H K S Y
Honey Bee Apis mellifera XP_395198 782 90486 S241 L A S L K G S S K K Y I V L A
Nematode Worm Caenorhab. elegans Q19426 796 92627 Y252 E K I P I D R Y H D F V V D N
Sea Urchin Strong. purpuratus NP_001157279 829 93116 F276 K D L V T R R F K Y H K K K T
Poplar Tree Populus trichocarpa XP_002315613 845 96641 P280 H Y S G F R T P H I H N L S D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 P278 H Y S G F K T P H I Y N L S D
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 I290 N P G N F H Y I Q K T F D L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. N.A. N.A. 6.6 0 N.A. 6.6 20 20 0
P-Site Similarity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. N.A. N.A. 20 6.6 N.A. 13.3 26.6 26.6 6.6
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 40 N.A. N.A. 46.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 27 7 0 14 0 0 7 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 20 0 0 0 7 0 0 0 7 0 0 7 7 14 % D
% Glu: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 20 0 0 7 7 0 27 14 14 0 0 % F
% Gly: 20 7 7 14 0 27 0 20 0 0 0 0 0 0 14 % G
% His: 14 0 7 7 0 7 14 0 20 0 14 7 0 0 0 % H
% Ile: 0 0 7 7 7 0 0 7 0 20 0 7 0 0 0 % I
% Lys: 7 14 0 20 7 27 7 0 20 14 0 7 14 7 0 % K
% Leu: 7 0 7 7 0 0 0 0 7 0 7 0 20 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 0 0 14 0 20 0 20 14 7 0 27 % N
% Pro: 7 7 20 7 14 0 0 14 0 0 0 0 0 14 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % Q
% Arg: 0 7 0 0 0 14 14 0 7 0 0 0 0 0 0 % R
% Ser: 0 7 20 14 14 0 27 7 14 7 7 14 0 40 14 % S
% Thr: 20 0 14 0 7 0 14 0 0 0 14 0 20 0 20 % T
% Val: 7 0 0 20 0 7 0 7 0 20 0 20 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 20 0 14 0 % W
% Tyr: 0 14 7 0 20 14 14 34 0 27 14 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _