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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOGS All Species: 55.76
Human Site: Y749 Identified Species: 87.62
UniProt: Q13724 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13724 NP_001139630.1 837 91918 Y749 N S E H D P P Y W R G A V W L
Chimpanzee Pan troglodytes XP_001159538 837 91907 Y749 N S E H D P P Y W R G A V W L
Rhesus Macaque Macaca mulatta XP_001109499 837 92099 Y749 N S E H D P P Y W R G A V W L
Dog Lupus familis XP_540220 836 92340 Y748 N S E H D P P Y W R G A V W L
Cat Felis silvestris
Mouse Mus musculus Q80UM7 834 91813 Y746 N T E H D P P Y W R G A V W L
Rat Rattus norvegicus O88941 834 91853 Y746 N T E H D P P Y W R G A V W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001121329 826 93558 Y738 N T E H D A P Y W R G P V W I
Zebra Danio Brachydanio rerio NP_001073659 841 96206 Y753 N T E H D A P Y W R G P I W I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572707 849 96131 Y761 N T E H D P P Y W R G P I W I
Honey Bee Apis mellifera XP_395198 782 90486 Y694 N T E H D A P Y W R G A I W M
Nematode Worm Caenorhab. elegans Q19426 796 92627 Y706 N T E H D P P Y W R G Y I W I
Sea Urchin Strong. purpuratus NP_001157279 829 93116 Y741 N T E H D A P Y W R G A V W I
Poplar Tree Populus trichocarpa XP_002315613 845 96641 Y756 N T E H D P P Y W R G P I W M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176916 852 97616 Y761 N T E H D A P Y W R G P I W M
Baker's Yeast Sacchar. cerevisiae P53008 833 96488 I747 E N Y W R G P I W M N I N Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 89.7 N.A. 86.5 85.1 N.A. N.A. N.A. 49.7 48.1 N.A. 41.7 38.1 36.4 46
Protein Similarity: 100 99.5 98 93 N.A. 90.8 90.4 N.A. N.A. N.A. 65.2 63.9 N.A. 55.3 54.9 51.6 62.2
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 73.3 66.6 N.A. 73.3 73.3 73.3 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 86.6 N.A. 93.3 93.3 93.3 93.3
Percent
Protein Identity: 40.1 N.A. N.A. 38.7 23.6 N.A.
Protein Similarity: 57.1 N.A. N.A. 55.2 41.7 N.A.
P-Site Identity: 73.3 N.A. N.A. 66.6 20 N.A.
P-Site Similarity: 93.3 N.A. N.A. 86.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 34 0 0 0 0 0 54 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 94 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 7 0 94 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 94 0 0 0 0 % G
% His: 0 0 0 94 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 7 40 0 34 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 20 % M
% Asn: 94 7 0 0 0 0 0 0 0 0 7 0 7 0 0 % N
% Pro: 0 0 0 0 0 60 100 0 0 0 0 34 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 94 0 0 0 0 0 % R
% Ser: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 100 0 0 0 0 94 0 % W
% Tyr: 0 0 7 0 0 0 0 94 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _