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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBA3C
All Species:
40.91
Human Site:
S439
Identified Species:
75
UniProt:
Q13748
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13748
NP_005992.1
450
49960
S439
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Chimpanzee
Pan troglodytes
Q5R1W4
451
50117
S439
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001110230
721
79213
S710
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Dog
Lupus familis
XP_534765
450
49927
S439
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P05214
450
49941
S439
Y
E
E
V
G
V
D
S
V
E
A
E
A
E
E
Rat
Rattus norvegicus
Q6AYZ1
449
49919
S439
Y
E
E
V
G
A
D
S
A
E
G
D
D
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09644
448
49930
D438
D
Y
E
E
V
G
L
D
S
Y
E
D
E
E
E
Frog
Xenopus laevis
P08537
449
49861
S439
Y
E
E
V
G
A
D
S
A
D
A
E
D
E
G
Zebra Danio
Brachydanio rerio
NP_919369
449
49935
S439
Y
E
E
V
G
A
E
S
V
E
G
E
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P06603
450
49890
S439
Y
E
E
V
G
M
D
S
G
D
G
E
G
E
G
Honey Bee
Apis mellifera
XP_391936
450
49946
S439
Y
E
E
V
G
M
D
S
A
E
G
E
G
E
G
Nematode Worm
Caenorhab. elegans
P34690
448
49895
S437
Y
E
E
V
G
A
D
S
N
E
G
G
E
E
E
Sea Urchin
Strong. purpuratus
XP_001178141
451
50085
S439
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
62.4
99.7
N.A.
100
96.2
N.A.
N.A.
93.5
96.4
96.2
N.A.
97.5
97.7
87.1
98.6
Protein Similarity:
100
98.4
62.4
100
N.A.
100
98.4
N.A.
N.A.
96
98.6
98.6
N.A.
98.2
98.2
94
98.8
P-Site Identity:
100
86.6
100
100
N.A.
100
60
N.A.
N.A.
20
66.6
66.6
N.A.
60
66.6
66.6
86.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
66.6
N.A.
N.A.
26.6
73.3
73.3
N.A.
73.3
73.3
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
0
0
24
0
39
0
31
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
85
8
0
16
0
16
24
0
0
% D
% Glu:
0
93
100
8
0
0
8
0
0
77
8
77
16
100
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
93
8
0
0
8
0
54
8
31
0
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
93
8
47
0
0
54
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _