KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMC2
All Species:
21.82
Human Site:
S226
Identified Species:
48
UniProt:
Q13753
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13753
NP_005553.2
1193
130976
S226
K
A
V
Q
R
N
G
S
P
A
K
L
Q
W
S
Chimpanzee
Pan troglodytes
XP_001162731
1193
131041
S226
K
A
V
Q
R
N
G
S
P
A
K
L
Q
W
S
Rhesus Macaque
Macaca mulatta
XP_001114169
1193
131267
S226
K
A
V
Q
R
N
G
S
P
A
K
L
Q
W
S
Dog
Lupus familis
XP_537156
1496
165723
S421
R
V
E
Q
R
D
G
S
E
A
S
L
E
W
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61092
1191
130142
A226
K
A
V
Q
R
N
G
A
P
A
K
L
H
W
S
Rat
Rattus norvegicus
P15800
1801
196455
L628
A
M
D
Y
D
L
L
L
R
W
E
P
Q
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516019
1183
130979
S227
R
A
V
L
R
N
G
S
P
R
Q
L
Q
W
S
Chicken
Gallus gallus
XP_422285
1177
127403
S224
T
G
V
H
E
D
R
S
P
T
E
L
Q
W
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVF0
1593
176187
S518
K
G
K
Q
R
D
D
S
S
V
P
V
Q
W
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15215
1639
182321
R553
T
A
A
D
L
N
Q
R
E
V
D
I
K
Y
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18823
1535
170219
L527
A
G
Q
N
R
I
G
L
Q
D
T
Q
W
A
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.2
33.3
N.A.
83.4
21.1
N.A.
63.8
56.9
N.A.
29.2
N.A.
25.4
N.A.
22.7
N.A.
Protein Similarity:
100
99.6
98.4
49.8
N.A.
91.3
33.5
N.A.
77.5
73.3
N.A.
45.5
N.A.
39.7
N.A.
38.7
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
86.6
6.6
N.A.
73.3
46.6
N.A.
46.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
13.3
N.A.
86.6
60
N.A.
60
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
55
10
0
0
0
0
10
0
46
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
28
10
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
0
19
0
19
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
0
0
0
0
64
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
46
0
10
0
0
0
0
0
0
0
37
0
10
0
0
% K
% Leu:
0
0
0
10
10
10
10
19
0
0
0
64
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
55
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
55
0
10
10
0
0
10
% P
% Gln:
0
0
10
55
0
0
10
0
10
0
10
10
64
0
0
% Q
% Arg:
19
0
0
0
73
0
10
10
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
10
0
10
0
0
0
73
% S
% Thr:
19
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
10
55
0
0
0
0
0
0
19
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
10
73
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _