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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
33.94
Human Site:
S149
Identified Species:
67.88
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S149
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
V102
S
F
T
L
T
I
T
V
F
T
N
P
T
Q
V
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S232
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Dog
Lupus familis
XP_544492
414
44288
R149
D
R
F
G
E
L
E
R
L
R
M
R
V
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
S150
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Rat
Rattus norvegicus
Q63046
450
48538
S145
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
T75
S
G
R
G
K
S
F
T
L
T
I
T
V
F
T
Frog
Xenopus laevis
Q6PF39
462
50351
S145
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
S142
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
S141
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
S370
G
R
S
G
R
G
K
S
F
T
L
T
I
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
C43
E
R
K
S
M
P
R
C
K
C
L
P
L
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
20
N.A.
100
100
N.A.
N.A.
20
100
100
100
100
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
40
N.A.
100
100
N.A.
N.A.
46.6
100
100
100
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
9
0
75
0
0
0
0
9
0
% F
% Gly:
67
9
0
84
0
67
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
9
0
67
0
0
% I
% Lys:
0
0
9
0
9
0
67
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
9
0
0
17
0
75
0
9
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
17
0
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
84
9
0
67
0
9
9
0
9
0
9
0
0
0
% R
% Ser:
17
0
67
9
0
9
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
9
0
9
9
0
84
0
75
9
75
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
17
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _