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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
14.55
Human Site:
S395
Identified Species:
29.09
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S395
V
E
A
D
G
S
H
S
N
S
P
T
A
L
S
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
N342
E
A
D
G
S
H
S
N
S
P
T
A
L
S
T
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S481
V
E
A
D
G
S
H
S
N
S
P
T
A
L
S
Dog
Lupus familis
XP_544492
414
44288
N395
E
A
D
G
S
H
S
N
S
P
T
A
L
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
N390
E
A
D
G
S
H
S
N
S
P
T
A
L
S
T
Rat
Rattus norvegicus
Q63046
450
48538
T404
P
R
I
L
P
P
C
T
N
A
S
T
G
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
N315
D
A
D
G
S
H
S
N
S
P
T
T
M
T
T
Frog
Xenopus laevis
Q6PF39
462
50351
S442
V
E
A
E
G
S
H
S
N
S
P
T
N
M
G
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
A399
N
Q
S
D
G
V
D
A
D
G
S
H
S
N
S
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
S387
V
E
A
D
G
S
H
S
N
S
P
T
A
M
N
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
A647
A
T
D
P
Y
Q
T
A
G
Y
G
G
G
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
A283
A
G
A
S
V
Y
K
A
V
K
L
R
D
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
13.3
N.A.
N.A.
6.6
73.3
20
86.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
20
N.A.
20
33.3
N.A.
N.A.
26.6
86.6
53.3
100
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
34
42
0
0
0
0
25
0
9
0
25
25
9
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
42
34
0
0
9
0
9
0
0
0
9
0
0
% D
% Glu:
25
34
0
9
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
34
42
0
0
0
9
9
9
9
17
0
9
% G
% His:
0
0
0
0
0
34
34
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
9
0
25
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% M
% Asn:
9
0
0
0
0
0
0
34
42
0
0
0
9
17
17
% N
% Pro:
9
0
0
9
9
9
0
0
0
34
34
0
0
0
0
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
9
9
34
34
34
34
34
34
17
0
9
25
25
% S
% Thr:
0
9
0
0
0
0
9
9
0
0
34
50
0
9
42
% T
% Val:
34
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _