Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNX3 All Species: 31.21
Human Site: T155 Identified Species: 62.42
UniProt: Q13761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13761 NP_001026850.1 415 44356 T155 K S F T L T I T V F T N P T Q
Chimpanzee Pan troglodytes XP_001168112 361 38974 Q108 T V F T N P T Q V A T Y H R A
Rhesus Macaque Macaca mulatta XP_001113682 501 52667 T238 K S F T L T I T V F T N P T Q
Dog Lupus familis XP_544492 414 44288 T155 E R L R M R V T P S T P S P R
Cat Felis silvestris
Mouse Mus musculus Q64131 409 43610 T156 K S F T L T I T V F T N P T Q
Rat Rattus norvegicus Q63046 450 48538 T151 K S F T L T I T V F T N P P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232978 334 36473 F81 F T L T I T V F T N P T Q V A
Frog Xenopus laevis Q6PF39 462 50351 T151 K S F T L T I T V F T N P P Q
Zebra Danio Brachydanio rerio NP_571679 424 45996 T148 K S F T L T I T V F T G P P Q
Tiger Blowfish Takifugu rubipres NP_001092121 407 44638 T147 K S F T L T I T V F T G P P Q
Fruit Fly Dros. melanogaster Q9W349 826 84703 T376 K S F T L T I T V A T S P P Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN1 302 31144 P49 R C K C L P L P A V E G W G V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 63 48.6 N.A. 91.5 59.5 N.A. N.A. 68.9 56.9 68.1 67.9 23.3 N.A. N.A. N.A.
Protein Similarity: 100 86.9 68.2 56.1 N.A. 94.6 70.4 N.A. N.A. 74.2 69 75.2 77.3 33.1 N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 13.3 N.A. 100 93.3 N.A. N.A. 13.3 93.3 86.6 86.6 80 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 40 N.A. 100 93.3 N.A. N.A. 33.3 93.3 86.6 86.6 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 30.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 17 0 0 0 0 17 % A
% Cys: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 9 0 75 0 0 0 0 9 0 59 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 25 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 9 0 67 0 0 0 0 0 0 0 0 % I
% Lys: 67 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 17 0 75 0 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 0 42 0 0 0 % N
% Pro: 0 0 0 0 0 17 0 9 9 0 9 9 67 50 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 67 % Q
% Arg: 9 9 0 9 0 9 0 0 0 0 0 0 0 9 9 % R
% Ser: 0 67 0 0 0 0 0 0 0 9 0 9 9 0 0 % S
% Thr: 9 9 0 84 0 75 9 75 9 0 84 9 0 25 0 % T
% Val: 0 9 0 0 0 0 17 0 75 9 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _