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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
7.27
Human Site:
T257
Identified Species:
14.55
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
T257
R
S
F
P
T
L
P
T
L
T
E
S
R
F
P
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
L204
S
F
P
T
L
P
T
L
T
E
S
R
F
P
D
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S343
S
C
P
T
V
V
D
S
L
F
P
L
F
E
S
Dog
Lupus familis
XP_544492
414
44288
P257
R
Q
F
D
R
S
F
P
A
L
Q
T
F
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
T252
Q
F
D
R
S
F
P
T
L
Q
S
L
T
E
S
Rat
Rattus norvegicus
Q63046
450
48538
S266
Q
Y
L
G
S
I
T
S
S
V
H
P
A
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
S177
D
P
R
Q
F
D
R
S
F
P
T
L
P
T
L
Frog
Xenopus laevis
Q6PF39
462
50351
A304
S
G
A
S
D
L
T
A
F
S
D
P
R
V
G
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
S261
D
L
F
Q
Q
R
T
S
F
P
S
L
S
P
L
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
T249
D
L
R
P
W
P
G
T
T
D
L
F
Q
Q
R
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
S509
S
N
Y
S
S
P
N
S
T
I
N
S
D
C
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
H145
I
A
F
A
A
L
R
H
F
P
W
L
Q
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
13.3
N.A.
20
6.6
N.A.
N.A.
0
13.3
6.6
13.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
20
26.6
N.A.
33.3
33.3
N.A.
N.A.
6.6
26.6
13.3
20
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
9
0
0
9
9
0
0
0
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
25
0
9
9
9
9
9
0
0
9
9
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
9
0
0
17
9
% E
% Phe:
0
17
34
0
9
9
9
0
34
9
0
9
25
9
0
% F
% Gly:
0
9
0
9
0
0
9
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
17
9
0
9
25
0
9
25
9
9
42
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
0
0
9
0
0
0
0
% N
% Pro:
0
9
17
17
0
25
17
9
0
25
9
17
9
17
25
% P
% Gln:
17
9
0
17
9
0
0
0
0
9
9
0
17
9
9
% Q
% Arg:
17
0
17
9
9
9
17
0
0
0
0
9
17
0
9
% R
% Ser:
34
9
0
17
25
9
0
42
9
9
25
17
9
0
17
% S
% Thr:
0
0
0
17
9
0
34
25
25
9
9
9
9
25
0
% T
% Val:
0
0
0
0
9
9
0
0
0
9
0
0
0
17
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _