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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHROOM2
All Species:
4.24
Human Site:
S433
Identified Species:
13.33
UniProt:
Q13796
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13796
NP_001640.1
1616
176410
S433
G
R
H
P
P
L
Y
S
D
H
S
P
L
C
A
Chimpanzee
Pan troglodytes
XP_520924
849
91710
Rhesus Macaque
Macaca mulatta
XP_001094662
1780
193674
N476
G
R
P
T
C
A
V
N
T
K
A
E
D
P
G
Dog
Lupus familis
XP_548854
1630
179595
S443
C
Q
H
P
R
Q
Y
S
D
E
S
P
F
C
H
Cat
Felis silvestris
Mouse
Mus musculus
A2ALU4
1481
164685
D406
D
C
R
W
L
C
S
D
D
R
A
G
R
P
S
Rat
Rattus norvegicus
Q7TP36
1423
157971
D360
S
V
N
Q
K
L
D
D
R
G
R
S
H
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514972
1675
186527
T433
G
G
Q
P
E
P
S
T
E
R
F
C
G
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q27IV2
1788
200696
H465
A
H
G
E
H
E
Y
H
N
H
F
N
I
A
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.3
25.8
71.7
N.A.
63.6
55.6
N.A.
56.8
N.A.
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.7
40.3
78.5
N.A.
69.9
63.1
N.A.
66.6
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
53.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
26.6
60
N.A.
20
13.3
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
13
0
0
0
0
25
0
0
13
13
% A
% Cys:
13
13
0
0
13
13
0
0
0
0
0
13
0
25
0
% C
% Asp:
13
0
0
0
0
0
13
25
38
0
0
0
13
0
0
% D
% Glu:
0
0
0
13
13
13
0
0
13
13
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
0
13
0
13
% F
% Gly:
38
13
13
0
0
0
0
0
0
13
0
13
13
0
13
% G
% His:
0
13
25
0
13
0
0
13
0
25
0
0
13
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
25
0
0
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
13
13
0
0
13
0
0
0
% N
% Pro:
0
0
13
38
13
13
0
0
0
0
0
25
0
25
0
% P
% Gln:
0
13
13
13
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
25
13
0
13
0
0
0
13
25
13
0
13
13
0
% R
% Ser:
13
0
0
0
0
0
25
25
0
0
25
13
0
0
38
% S
% Thr:
0
0
0
13
0
0
0
13
13
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
38
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _