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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLMH All Species: 39.7
Human Site: T249 Identified Species: 72.78
UniProt: Q13867 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13867 NP_000377.1 455 52562 T249 Y Q K I G P I T P L E F Y R E
Chimpanzee Pan troglodytes XP_511383 624 70401 T418 Y Q K I G P I T P L E F Y R E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537755 654 73702 T448 Y Q R I G P I T P L E F Y R E
Cat Felis silvestris
Mouse Mus musculus Q8R016 455 52493 T249 Y H K I G P I T P L Q F Y K E
Rat Rattus norvegicus P70645 454 52304 T249 Y H K V G P I T P L Q F Y K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509859 634 72431 T428 Y H K I G P V T P L E F Y R D
Chicken Gallus gallus P87362 455 52672 T249 Y H K F G P M T P V Q F Y N E
Frog Xenopus laevis NP_001089300 453 52300 T248 F C K I G P I T P Q D F Y K C
Zebra Danio Brachydanio rerio NP_956312 453 52201 T248 F H H L G P L T P L E F Y T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001096907 511 57742 S306 Y Q S I G P V S S L E F Y E R
Honey Bee Apis mellifera XP_001119959 455 52393 S250 Y N C I G P I S P V E F Y E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178956 404 45787 D234 T F T W E Y Y D K T K T Y Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q01532 483 55464 P282 I H T I K S T P L E F A S K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66 N.A. 66.6 N.A. 93.1 93.4 N.A. 61.6 75.3 73.4 71.4 N.A. 51 56.9 N.A. 50.9
Protein Similarity: 100 69.5 N.A. 68.9 N.A. 97.5 97.5 N.A. 68.1 87.9 88.1 87 N.A. 66.5 72.7 N.A. 66.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 73.3 N.A. 80 60 60 60 N.A. 60 60 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 93.3 80 80 80 N.A. 73.3 80 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 57.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 0 0 8 54 0 0 16 54 % E
% Phe: 16 8 0 8 0 0 0 0 0 0 8 85 0 0 0 % F
% Gly: 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 47 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 70 0 0 54 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 54 0 8 0 0 0 8 0 8 0 0 31 8 % K
% Leu: 0 0 0 8 0 0 8 0 8 62 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 85 0 8 77 0 0 0 0 0 0 % P
% Gln: 0 31 0 0 0 0 0 0 0 8 24 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 31 8 % R
% Ser: 0 0 8 0 0 8 0 16 8 0 0 0 8 0 0 % S
% Thr: 8 0 16 0 0 0 8 70 0 8 0 8 0 8 8 % T
% Val: 0 0 0 8 0 0 16 0 0 16 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 70 0 0 0 0 8 8 0 0 0 0 0 93 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _