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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC2
All Species:
33.03
Human Site:
Y206
Identified Species:
55.9
UniProt:
Q13868
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13868
NP_055100.2
293
32789
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
E
Chimpanzee
Pan troglodytes
XP_001165990
285
31976
E206
P
T
P
E
H
K
E
E
E
A
G
G
F
I
A
Rhesus Macaque
Macaca mulatta
XP_001106567
293
32714
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
E
Dog
Lupus familis
XP_850770
538
57965
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV3
293
32613
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
D
Rat
Rattus norvegicus
NP_001102422
293
32671
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507703
293
32690
Y206
N
N
G
F
I
W
I
Y
P
T
S
E
Q
K
E
Chicken
Gallus gallus
NP_001012816
294
32419
Y207
N
N
G
F
I
W
I
Y
P
T
P
E
Q
K
D
Frog
Xenopus laevis
NP_001085606
293
32342
C206
N
N
G
F
I
W
L
C
P
T
P
E
E
T
E
Zebra Danio
Brachydanio rerio
NP_001017572
254
28497
G179
L
Q
E
E
Q
A
G
G
F
Y
T
S
M
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611807
298
33606
S209
N
N
G
Y
I
W
I
S
P
T
K
G
Q
E
E
Honey Bee
Apis mellifera
XP_396929
295
33325
G211
N
N
G
Y
I
W
I
G
A
S
R
Q
D
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789513
291
32584
T203
N
N
G
Y
V
W
I
T
R
T
P
T
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38792
359
39409
R234
V
N
G
Y
I
W
L
R
K
T
S
Q
M
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
98.9
52.4
N.A.
93.8
94.8
N.A.
84.6
85.3
80.8
70.3
N.A.
55.3
55.9
N.A.
62.4
Protein Similarity:
100
97.2
99.6
53.7
N.A.
98.2
97.9
N.A.
91.8
92.8
92.1
80.8
N.A.
75.5
74.9
N.A.
81.5
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
73.3
0
N.A.
60
40
N.A.
53.3
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
86.6
93.3
80
6.6
N.A.
73.3
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
29
% D
% Glu:
0
0
8
15
0
0
8
8
8
0
0
58
15
22
50
% E
% Phe:
0
0
0
58
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
0
86
0
0
0
8
15
0
0
8
15
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
36
0
0
% H
% Ile:
0
0
0
0
79
0
72
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
8
0
8
0
0
50
0
% K
% Leu:
8
0
0
0
0
0
15
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
79
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
65
0
58
0
0
0
8
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
15
22
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
8
15
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
79
8
8
0
15
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
29
0
0
0
50
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _