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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLF5 All Species: 14.24
Human Site: T346 Identified Species: 28.48
UniProt: Q13887 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13887 NP_001721.2 457 50792 T346 H N P N L P T T L P V N S Q N
Chimpanzee Pan troglodytes XP_001136935 457 50773 T346 H N P N L P T T L P V N S Q N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849076 457 50925 T346 H N P N L P A T L P V N S Q S
Cat Felis silvestris
Mouse Mus musculus Q9Z0Z7 446 49735 T335 H N P N L P A T L P V N S P T
Rat Rattus norvegicus O35819 283 31823 S177 P S P G K V R S G T S G K S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516814 367 41217 S261 P A T L P I N S Q N I P T V R
Chicken Gallus gallus Q90WR8 771 80932 R584 Q P H Q E G K R L R R V A C T
Frog Xenopus laevis NP_001090064 374 41915 G268 Q F L H Q Q E G T Y F P P S P
Zebra Danio Brachydanio rerio XP_001344916 439 48402 A328 S H P T P A S A R P P T T T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097493 751 82329 A637 H H Q P G T A A H I A S L M S
Honey Bee Apis mellifera XP_001121583 542 59558 P426 P Q P S I M N P P H R I Q P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781216 287 32990 R181 K N N P D L E R R R I H H C N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 95.6 N.A. 89.5 28.8 N.A. 72.8 20.7 53.6 51.4 N.A. 27.1 28.4 N.A. 30.8
Protein Similarity: 100 99.5 N.A. 96.9 N.A. 92.1 42.2 N.A. 76.5 33.5 64.9 64.7 N.A. 37 41.3 N.A. 40.4
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 6.6 N.A. 0 6.6 0 13.3 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 80 20 N.A. 20 13.3 6.6 33.3 N.A. 26.6 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 25 17 0 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 17 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 9 9 9 0 9 9 0 0 9 0 0 17 % G
% His: 42 17 9 9 0 0 0 0 9 9 0 9 9 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 9 17 9 0 0 0 % I
% Lys: 9 0 0 0 9 0 9 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 9 9 34 9 0 0 42 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 42 9 34 0 0 17 0 0 9 0 34 0 0 25 % N
% Pro: 25 9 59 17 17 34 0 9 9 42 9 17 9 17 17 % P
% Gln: 17 9 9 9 9 9 0 0 9 0 0 0 9 25 0 % Q
% Arg: 0 0 0 0 0 0 9 17 17 17 17 0 0 0 9 % R
% Ser: 9 9 0 9 0 0 9 17 0 0 9 9 34 17 17 % S
% Thr: 0 0 9 9 0 9 17 34 9 9 0 9 17 9 17 % T
% Val: 0 0 0 0 0 9 0 0 0 0 34 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _