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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLF5
All Species:
9.09
Human Site:
Y374
Identified Species:
18.18
UniProt:
Q13887
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13887
NP_001721.2
457
50792
Y374
L
E
K
R
R
I
H
Y
C
D
Y
P
G
C
T
Chimpanzee
Pan troglodytes
XP_001136935
457
50773
Y374
L
E
K
R
R
I
H
Y
C
D
Y
P
G
C
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849076
457
50925
Y374
L
E
K
R
R
I
H
Y
C
D
Y
P
G
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z7
446
49735
F363
L
E
K
R
R
I
H
F
C
D
Y
N
G
C
T
Rat
Rattus norvegicus
O35819
283
31823
N205
R
V
H
R
C
H
F
N
G
C
R
K
V
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516814
367
41217
G289
I
H
Y
C
D
Y
P
G
C
T
K
V
Y
T
K
Chicken
Gallus gallus
Q90WR8
771
80932
I612
L
G
K
K
K
Q
H
I
C
H
I
P
G
C
G
Frog
Xenopus laevis
NP_001090064
374
41915
P296
L
L
Q
G
L
N
P
P
P
S
Y
A
A
T
I
Zebra Danio
Brachydanio rerio
XP_001344916
439
48402
H356
L
E
K
R
R
I
H
H
C
D
F
P
G
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097493
751
82329
H665
L
E
K
R
R
I
H
H
C
D
F
V
G
C
S
Honey Bee
Apis mellifera
XP_001121583
542
59558
H454
L
E
K
R
R
V
H
H
C
D
F
I
G
C
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781216
287
32990
H209
L
K
A
H
Q
R
I
H
T
G
E
K
P
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
95.6
N.A.
89.5
28.8
N.A.
72.8
20.7
53.6
51.4
N.A.
27.1
28.4
N.A.
30.8
Protein Similarity:
100
99.5
N.A.
96.9
N.A.
92.1
42.2
N.A.
76.5
33.5
64.9
64.7
N.A.
37
41.3
N.A.
40.4
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
13.3
N.A.
6.6
46.6
13.3
80
N.A.
73.3
73.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
13.3
N.A.
13.3
60
20
93.3
N.A.
93.3
93.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
9
9
0
0
0
75
9
0
0
0
67
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
59
0
0
0
0
0
% D
% Glu:
0
59
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
25
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
9
9
9
0
0
67
0
9
% G
% His:
0
9
9
9
0
9
67
34
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
50
9
9
0
0
9
9
0
0
9
% I
% Lys:
0
9
67
9
9
0
0
0
0
0
9
17
0
0
17
% K
% Leu:
84
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
9
9
0
0
42
9
0
0
% P
% Gln:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
67
59
9
0
0
0
0
9
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
9
9
0
0
0
17
50
% T
% Val:
0
9
0
0
0
9
0
0
0
0
0
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
25
0
0
42
0
9
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _