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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLF5 All Species: 13.64
Human Site: Y377 Identified Species: 27.27
UniProt: Q13887 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13887 NP_001721.2 457 50792 Y377 R R I H Y C D Y P G C T K V Y
Chimpanzee Pan troglodytes XP_001136935 457 50773 Y377 R R I H Y C D Y P G C T K V Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849076 457 50925 Y377 R R I H Y C D Y P G C T K V Y
Cat Felis silvestris
Mouse Mus musculus Q9Z0Z7 446 49735 Y366 R R I H F C D Y N G C T K V Y
Rat Rattus norvegicus O35819 283 31823 R208 R C H F N G C R K V Y T K S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516814 367 41217 K292 C D Y P G C T K V Y T K S S H
Chicken Gallus gallus Q90WR8 771 80932 I615 K K Q H I C H I P G C G K V Y
Frog Xenopus laevis NP_001090064 374 41915 Y299 G L N P P P S Y A A T I A C K
Zebra Danio Brachydanio rerio XP_001344916 439 48402 F359 R R I H H C D F P G C K K V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097493 751 82329 F668 R R I H H C D F V G C S K V Y
Honey Bee Apis mellifera XP_001121583 542 59558 F457 R R V H H C D F I G C T K V Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781216 287 32990 E212 H Q R I H T G E K P Y R C T W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 95.6 N.A. 89.5 28.8 N.A. 72.8 20.7 53.6 51.4 N.A. 27.1 28.4 N.A. 30.8
Protein Similarity: 100 99.5 N.A. 96.9 N.A. 92.1 42.2 N.A. 76.5 33.5 64.9 64.7 N.A. 37 41.3 N.A. 40.4
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 20 N.A. 6.6 53.3 6.6 80 N.A. 73.3 73.3 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 20 N.A. 13.3 66.6 6.6 93.3 N.A. 93.3 93.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 9 0 0 9 0 0 % A
% Cys: 9 9 0 0 0 75 9 0 0 0 67 0 9 9 0 % C
% Asp: 0 9 0 0 0 0 59 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 9 0 0 25 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 9 9 9 0 0 67 0 9 0 0 0 % G
% His: 9 0 9 67 34 0 9 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 50 9 9 0 0 9 9 0 0 9 0 0 0 % I
% Lys: 9 9 0 0 0 0 0 9 17 0 0 17 75 0 9 % K
% Leu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 17 9 9 0 0 42 9 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 67 59 9 0 0 0 0 9 0 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 0 0 0 9 9 17 9 % S
% Thr: 0 0 0 0 0 9 9 0 0 0 17 50 0 9 0 % T
% Val: 0 0 9 0 0 0 0 0 17 9 0 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 9 0 25 0 0 42 0 9 17 0 0 0 67 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _