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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2
All Species:
40.61
Human Site:
T138
Identified Species:
68.72
UniProt:
Q13888
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13888
NP_001506.1
395
44419
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Dog
Lupus familis
XP_535266
395
44483
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Rat
Rattus norvegicus
A0JN27
396
44685
T138
L
K
K
A
V
D
M
T
C
H
G
E
P
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
T213
L
K
K
A
V
D
M
T
C
L
G
E
P
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
T138
M
K
K
A
V
D
M
T
C
S
G
E
P
S
L
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
T138
L
R
K
A
V
D
S
T
C
V
G
E
P
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
S141
L
E
S
L
A
N
V
S
L
T
S
E
P
S
L
Honey Bee
Apis mellifera
XP_394997
405
45681
T139
V
Q
S
M
Q
Q
I
T
P
A
G
E
P
S
L
Nematode Worm
Caenorhab. elegans
P34567
376
41593
M124
K
A
D
R
L
T
M
M
T
G
N
I
R
V
L
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
P139
L
E
K
C
N
D
K
P
C
V
K
E
P
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
E203
L
K
S
I
R
K
Q
E
P
K
G
N
P
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.7
98.2
N.A.
96.9
96.4
N.A.
77.8
N.A.
84
81
N.A.
49
50.1
42.2
50.6
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
33.3
40
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
60
60
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
65
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
72
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
72
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
8
0
0
0
86
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
79
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
8
65
72
0
0
8
8
0
0
8
8
0
0
0
0
% K
% Leu:
79
0
0
8
8
0
0
0
8
8
0
0
0
0
100
% L
% Met:
8
0
0
8
0
0
65
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
15
0
0
0
93
0
0
% P
% Gln:
0
8
0
0
8
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
22
0
0
0
8
8
0
8
8
0
0
93
0
% S
% Thr:
0
0
0
0
0
8
0
72
8
8
0
0
0
0
0
% T
% Val:
8
0
0
0
65
0
8
0
0
15
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _