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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2
All Species:
35.45
Human Site:
Y146
Identified Species:
60
UniProt:
Q13888
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13888
NP_001506.1
395
44419
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
I
A
M
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
M
A
M
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
M
A
M
Dog
Lupus familis
XP_535266
395
44483
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
M
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
M
A
M
Rat
Rattus norvegicus
A0JN27
396
44685
Y146
C
H
G
E
P
S
L
Y
N
S
L
S
M
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
Y221
C
L
G
E
P
S
L
Y
N
S
L
S
L
A
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
Y146
C
S
G
E
P
S
L
Y
N
S
L
N
L
A
L
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
Y146
C
V
G
E
P
S
L
Y
N
S
L
N
M
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
Q149
L
T
S
E
P
S
L
Q
N
G
L
D
L
A
L
Honey Bee
Apis mellifera
XP_394997
405
45681
Q147
P
A
G
E
P
S
L
Q
N
S
I
E
L
A
L
Nematode Worm
Caenorhab. elegans
P34567
376
41593
K132
T
G
N
I
R
V
L
K
E
S
L
N
T
L
T
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
Q147
C
V
K
E
P
S
L
Q
N
A
L
E
L
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
Q211
P
K
G
N
P
S
L
Q
N
A
L
E
M
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.7
98.2
N.A.
96.9
96.4
N.A.
77.8
N.A.
84
81
N.A.
49
50.1
42.2
50.6
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
73.3
73.3
N.A.
46.6
53.3
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
60
73.3
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
15
0
0
0
93
8
% A
% Cys:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
86
0
0
0
0
8
0
0
22
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
79
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
100
0
0
0
93
0
36
8
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
50
% M
% Asn:
0
0
8
8
0
0
0
0
93
0
0
22
0
0
0
% N
% Pro:
15
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
0
0
93
0
0
0
79
0
50
0
0
0
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% T
% Val:
0
15
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _