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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2
All Species:
35.45
Human Site:
Y183
Identified Species:
60
UniProt:
Q13888
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13888
NP_001506.1
395
44419
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Dog
Lupus familis
XP_535266
395
44483
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Rat
Rattus norvegicus
A0JN27
396
44685
Y183
T
C
D
P
S
N
I
Y
D
L
I
K
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
Y258
T
C
D
P
S
N
I
Y
D
L
I
K
S
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
Y183
T
C
D
P
T
N
I
Y
D
M
I
K
C
L
K
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
Y183
T
C
D
P
G
N
I
Y
E
L
I
K
T
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
N186
T
C
D
P
V
D
I
N
L
T
I
D
E
L
K
Honey Bee
Apis mellifera
XP_394997
405
45681
N184
T
C
D
P
G
D
I
N
E
T
I
K
N
M
K
Nematode Worm
Caenorhab. elegans
P34567
376
41593
R169
G
M
P
G
H
V
S
R
E
V
V
L
V
I
S
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
H184
T
C
D
P
G
N
I
H
D
T
I
Q
A
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
H248
T
T
D
P
G
D
I
H
Q
T
I
D
S
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.7
98.2
N.A.
96.9
96.4
N.A.
77.8
N.A.
84
81
N.A.
49
50.1
42.2
50.6
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
80
80
N.A.
53.3
53.3
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
60
73.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
86
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
93
0
0
22
0
0
65
0
0
15
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
22
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
29
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
93
0
0
0
93
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
79
% K
% Leu:
0
0
0
0
0
0
0
0
8
58
0
8
0
79
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
15
0
% M
% Asn:
0
0
0
0
0
72
0
15
0
0
0
0
8
0
8
% N
% Pro:
0
0
8
93
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
0
8
0
0
0
0
0
15
0
8
% S
% Thr:
93
8
0
0
8
0
0
0
0
29
0
0
50
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
8
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _