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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2
All Species:
33.33
Human Site:
Y228
Identified Species:
56.41
UniProt:
Q13888
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13888
NP_001506.1
395
44419
Y228
V
I
L
D
E
S
H
Y
K
E
L
L
T
H
H
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
Y228
V
I
L
D
E
S
H
Y
K
E
L
L
T
H
H
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
Y228
V
I
L
D
E
S
H
Y
K
E
L
L
T
H
H
Dog
Lupus familis
XP_535266
395
44483
Y228
V
I
L
D
E
S
H
Y
K
E
L
L
T
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
Y228
V
I
L
D
E
T
H
Y
K
E
L
L
A
H
H
Rat
Rattus norvegicus
A0JN27
396
44685
Y228
V
I
L
D
E
T
H
Y
K
E
L
L
A
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
Y303
V
I
L
D
E
S
H
Y
K
E
L
L
I
H
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
Y228
V
I
L
D
E
S
H
Y
K
E
L
L
M
H
H
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
F228
V
I
L
D
E
S
H
F
K
E
L
L
L
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
F231
A
V
L
D
D
A
H
F
R
D
Q
L
M
S
Q
Honey Bee
Apis mellifera
XP_394997
405
45681
Y229
V
A
L
D
D
K
H
Y
K
E
Q
L
N
M
H
Nematode Worm
Caenorhab. elegans
P34567
376
41593
E214
A
E
M
F
V
C
K
E
M
A
K
A
T
K
G
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
F229
V
I
L
D
E
T
H
F
K
E
L
L
M
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
D293
S
F
Y
K
I
L
L
D
E
T
H
L
K
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.7
98.2
N.A.
96.9
96.4
N.A.
77.8
N.A.
84
81
N.A.
49
50.1
42.2
50.6
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
93.3
N.A.
93.3
80
N.A.
26.6
60
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
93.3
N.A.
93.3
86.6
N.A.
66.6
66.6
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
8
0
0
0
8
0
8
15
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
86
15
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
72
0
0
8
8
79
0
0
0
15
0
% E
% Phe:
0
8
0
8
0
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
86
0
0
0
8
0
0
50
79
% H
% Ile:
0
72
0
0
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
8
8
0
79
0
8
0
8
8
0
% K
% Leu:
0
0
86
0
0
8
8
0
0
0
72
93
8
8
8
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
22
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
0
50
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
22
0
0
0
8
0
0
36
0
0
% T
% Val:
79
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _