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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H3
All Species:
35.15
Human Site:
S239
Identified Species:
64.44
UniProt:
Q13889
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13889
NP_001507.2
308
34378
S239
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Chimpanzee
Pan troglodytes
XP_001170519
308
34390
S239
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001117550
103
11541
Q35
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
V
Dog
Lupus familis
XP_534644
308
34397
S239
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD76
309
34225
S240
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Rat
Rattus norvegicus
Q561R7
309
34259
S240
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507590
311
34886
S242
L
P
D
Q
D
Q
R
S
Q
L
I
L
P
P
P
Chicken
Gallus gallus
XP_001235063
321
35185
S252
L
P
D
Q
E
Q
R
S
Q
L
V
L
P
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121894
296
33155
S227
L
P
D
A
E
Q
R
S
Q
L
L
L
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608574
299
33330
H229
L
P
A
P
Q
I
R
H
K
L
V
L
P
P
P
Honey Bee
Apis mellifera
XP_394705
292
32982
S221
L
P
D
P
N
V
R
S
K
L
V
F
P
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182337
313
34830
E241
L
P
S
P
S
Q
R
E
S
L
V
L
P
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12004
338
37439
P260
F
I
D
P
S
L
R
P
I
I
V
K
P
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.4
97
N.A.
93.1
93.1
N.A.
89.3
79.1
N.A.
68.8
N.A.
44.8
48
N.A.
61.3
Protein Similarity:
100
99.6
33.4
98.3
N.A.
95.7
96.4
N.A.
95.1
87.8
N.A.
81.8
N.A.
60.7
68.5
N.A.
74.7
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
86.6
N.A.
80
N.A.
53.3
60
N.A.
53.3
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
66.6
80
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
77
8
47
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
8
0
0
8
16
47
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% K
% Leu:
85
0
0
0
0
8
0
0
8
85
16
77
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
85
0
31
0
0
0
8
0
0
0
8
100
93
77
% P
% Gln:
0
0
8
54
16
70
0
8
62
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
93
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
16
0
8
70
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
39
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _