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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H3
All Species:
31.21
Human Site:
Y71
Identified Species:
57.22
UniProt:
Q13889
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13889
NP_001507.2
308
34378
Y71
I
Q
E
S
R
F
L
Y
P
G
K
N
G
R
L
Chimpanzee
Pan troglodytes
XP_001170519
308
34390
Y71
I
Q
E
S
R
F
L
Y
P
G
K
N
G
R
L
Rhesus Macaque
Macaca mulatta
XP_001117550
103
11541
Dog
Lupus familis
XP_534644
308
34397
Y71
I
Q
E
S
R
F
L
Y
P
G
K
N
G
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD76
309
34225
Y71
I
Q
E
S
R
L
L
Y
P
G
K
N
G
G
L
Rat
Rattus norvegicus
Q561R7
309
34259
Y71
I
Q
E
S
R
F
L
Y
P
G
K
N
G
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507590
311
34886
Y73
I
Q
E
S
R
F
L
Y
P
G
K
N
W
K
L
Chicken
Gallus gallus
XP_001235063
321
35185
Y84
T
Q
E
S
R
F
L
Y
P
G
K
R
W
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121894
296
33155
Y63
L
A
V
I
T
S
L
Y
H
E
S
H
F
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608574
299
33330
H68
L
A
V
V
S
C
S
H
H
A
T
N
F
L
Y
Honey Bee
Apis mellifera
XP_394705
292
32982
S60
L
A
V
I
A
C
H
S
H
G
A
K
F
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182337
313
34830
Y76
T
N
E
S
R
F
L
Y
P
K
K
T
S
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12004
338
37439
Y87
S
Q
G
I
K
Y
L
Y
P
E
S
T
S
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.4
97
N.A.
93.1
93.1
N.A.
89.3
79.1
N.A.
68.8
N.A.
44.8
48
N.A.
61.3
Protein Similarity:
100
99.6
33.4
98.3
N.A.
95.7
96.4
N.A.
95.1
87.8
N.A.
81.8
N.A.
60.7
68.5
N.A.
74.7
P-Site Identity:
100
100
0
93.3
N.A.
86.6
100
N.A.
86.6
66.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
53.3
P-Site Similarity:
100
100
0
100
N.A.
86.6
100
N.A.
93.3
66.6
N.A.
26.6
N.A.
20
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
8
0
0
0
0
8
8
0
0
16
8
% A
% Cys:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
62
0
0
0
0
0
0
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
54
0
0
0
0
0
0
24
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
62
0
0
39
8
0
% G
% His:
0
0
0
0
0
0
8
8
24
0
0
8
0
0
0
% H
% Ile:
47
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
62
8
0
16
0
% K
% Leu:
24
0
0
0
0
8
77
0
0
0
0
0
0
24
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
54
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% P
% Gln:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
62
0
0
0
0
0
0
8
0
24
0
% R
% Ser:
8
0
0
62
8
8
8
8
0
0
16
0
16
0
8
% S
% Thr:
16
0
0
0
8
0
0
0
0
0
8
16
0
0
0
% T
% Val:
0
0
24
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% W
% Tyr:
0
0
0
0
0
8
0
77
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _