KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BYSL
All Species:
47.27
Human Site:
Y250
Identified Species:
74.29
UniProt:
Q13895
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13895
NP_004044.3
437
49601
Y250
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Chimpanzee
Pan troglodytes
XP_518469
323
36415
I150
A
R
R
T
L
A
D
I
I
M
E
K
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001085599
438
49814
Y250
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Dog
Lupus familis
XP_532135
573
64755
Y386
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
O54825
436
49765
Y249
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Rat
Rattus norvegicus
Q80WL2
436
49993
Y249
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418047
388
44132
E204
I
P
A
L
S
N
W
E
Q
I
L
Y
I
T
E
Frog
Xenopus laevis
NP_001085058
431
49284
Y247
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Zebra Danio
Brachydanio rerio
NP_957400
422
48101
Y233
E
R
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51406
436
49948
Y231
Q
A
M
A
Q
R
F
Y
N
L
V
L
L
P
R
Honey Bee
Apis mellifera
XP_397030
433
50344
Y242
E
K
M
A
Q
R
F
Y
N
L
I
L
L
P
R
Nematode Worm
Caenorhab. elegans
Q20932
449
51602
Y252
P
K
M
C
Q
R
F
Y
T
L
V
L
L
P
R
Sea Urchin
Strong. purpuratus
XP_001175650
430
49345
Y244
I
R
M
T
R
K
F
Y
N
L
I
L
L
P
R
Poplar Tree
Populus trichocarpa
XP_002330743
443
51017
Y231
A
K
K
A
E
R
F
Y
R
L
V
L
L
P
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38333
483
55118
I279
A
K
E
S
Q
K
F
I
N
L
I
L
L
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.9
97.4
71.7
N.A.
90.6
90.6
N.A.
N.A.
66.8
73.2
73.2
N.A.
51.7
59.2
49.4
57.2
Protein Similarity:
100
73.9
98.4
74
N.A.
93.5
93.5
N.A.
N.A.
74.8
85.8
84.2
N.A.
68.6
75.7
67.7
74.3
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
0
100
100
N.A.
86.6
86.6
73.3
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
26.6
100
100
N.A.
93.3
100
80
86.6
Percent
Protein Identity:
44.4
N.A.
N.A.
N.A.
35.4
N.A.
Protein Similarity:
65.9
N.A.
N.A.
N.A.
56.5
N.A.
P-Site Identity:
66.6
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
7
7
67
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
7
0
7
0
0
7
0
0
7
0
0
7
14
% E
% Phe:
0
0
0
0
0
0
87
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
0
0
14
7
7
20
0
7
0
0
% I
% Lys:
0
27
7
0
0
14
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
7
7
0
0
0
0
87
7
87
94
0
0
% L
% Met:
0
0
74
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
74
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
0
0
0
0
0
0
80
0
% P
% Gln:
7
0
0
0
74
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
60
7
0
7
74
0
0
7
0
0
0
0
0
87
% R
% Ser:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
14
0
0
0
0
7
0
0
0
0
14
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _