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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BYSL All Species: 34.55
Human Site: Y354 Identified Species: 54.29
UniProt: Q13895 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13895 NP_004044.3 437 49601 Y354 D K K Y A L P Y R V L D A L V
Chimpanzee Pan troglodytes XP_518469 323 36415 M245 A S N L K E R M A Q R F Y N L
Rhesus Macaque Macaca mulatta XP_001085599 438 49814 Y354 D K K Y A L P Y R V L D A L V
Dog Lupus familis XP_532135 573 64755 Y490 D K K Y A L P Y R V L D A L V
Cat Felis silvestris
Mouse Mus musculus O54825 436 49765 Y353 D K K Y A L P Y R V L D A L V
Rat Rattus norvegicus Q80WL2 436 49993 Y353 D K K Y A L P Y R V L D A L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418047 388 44132 K304 I I G S I L T K C S I P V L H
Frog Xenopus laevis NP_001085058 431 49284 F351 D K K Y A L P F R V L D A L L
Zebra Danio Brachydanio rerio NP_957400 422 48101 F337 D K K Y A L P F R V L D A L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P51406 436 49948 Y335 D K R Y A L P Y R V V D A A V
Honey Bee Apis mellifera XP_397030 433 50344 Y346 D K K Y A L P Y R V I D A V V
Nematode Worm Caenorhab. elegans Q20932 449 51602 Y356 D K K Y A L P Y R A V D G V V
Sea Urchin Strong. purpuratus XP_001175650 430 49345 F348 D K K Y A L P F R V I D A V V
Poplar Tree Populus trichocarpa XP_002330743 443 51017 F335 D K K Y A L P F R V L D A V V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38333 483 55118 Y384 D K K Y A L P Y Q T V D D C V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.9 97.4 71.7 N.A. 90.6 90.6 N.A. N.A. 66.8 73.2 73.2 N.A. 51.7 59.2 49.4 57.2
Protein Similarity: 100 73.9 98.4 74 N.A. 93.5 93.5 N.A. N.A. 74.8 85.8 84.2 N.A. 68.6 75.7 67.7 74.3
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. 13.3 86.6 93.3 N.A. 80 86.6 73.3 80
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 20 100 100 N.A. 93.3 100 86.6 100
Percent
Protein Identity: 44.4 N.A. N.A. N.A. 35.4 N.A.
Protein Similarity: 65.9 N.A. N.A. N.A. 56.5 N.A.
P-Site Identity: 86.6 N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: 100 N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 87 0 0 0 7 7 0 0 74 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % C
% Asp: 87 0 0 0 0 0 0 0 0 0 0 87 7 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 27 0 0 0 7 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 7 0 0 7 0 0 0 0 0 20 0 0 0 0 % I
% Lys: 0 87 80 0 7 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 7 0 94 0 0 0 0 54 0 0 54 14 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 87 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 7 0 80 0 7 0 0 0 0 % R
% Ser: 0 7 0 7 0 0 0 0 0 7 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 74 20 0 7 27 80 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 87 0 0 0 60 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _