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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1C
All Species:
2.12
Human Site:
S1535
Identified Species:
6.67
UniProt:
Q13936
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13936
NP_000710.5
2221
248892
S1535
D
Y
L
T
R
D
W
S
I
L
G
P
H
H
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117926
2225
248451
I1568
I
N
L
F
V
A
V
I
M
D
N
F
D
Y
L
Dog
Lupus familis
XP_534932
2114
236979
A1476
D
E
F
K
R
I
W
A
E
Y
D
P
E
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q01815
2139
240120
A1502
D
E
F
K
R
I
W
A
E
Y
D
P
E
A
K
Rat
Rattus norvegicus
P22002
2169
243464
A1531
D
E
F
K
R
I
W
A
E
Y
D
P
E
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
K1515
P
H
H
L
D
E
F
K
R
I
W
S
E
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571975
2168
243196
K1515
P
H
H
L
D
E
F
K
R
I
W
A
E
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24270
2516
276682
S1753
E
I
K
S
K
D
T
S
Q
I
A
E
C
D
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94
90.9
N.A.
91.2
90.5
N.A.
N.A.
66.4
N.A.
76.5
N.A.
44.4
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
95.3
92.2
N.A.
92.9
92.4
N.A.
N.A.
76.6
N.A.
84.1
N.A.
57.2
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
26.6
N.A.
26.6
26.6
N.A.
N.A.
0
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
33.3
N.A.
33.3
33.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
38
0
0
13
13
0
38
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
50
0
0
0
25
25
0
0
0
13
38
0
13
13
25
% D
% Glu:
13
38
0
0
0
25
0
0
38
0
0
13
63
0
0
% E
% Phe:
0
0
38
13
0
0
25
0
0
0
0
13
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% G
% His:
0
25
25
0
0
0
0
0
0
0
0
0
13
13
0
% H
% Ile:
13
13
0
0
0
38
0
13
13
38
0
0
0
0
13
% I
% Lys:
0
0
13
38
13
0
0
25
0
0
0
0
0
0
38
% K
% Leu:
0
0
25
25
0
0
0
0
0
13
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
25
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
0
25
0
0
0
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
25
0
0
0
13
0
0
0
% S
% Thr:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
50
0
0
0
25
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
0
0
38
0
0
0
38
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _