KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1C
All Species:
11.82
Human Site:
S2214
Identified Species:
37.14
UniProt:
Q13936
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13936
NP_000710.5
2221
248892
S2214
S
E
E
E
L
Q
D
S
R
V
Y
V
S
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117926
2225
248451
S2218
S
E
E
E
L
Q
D
S
R
V
Y
V
S
S
L
Dog
Lupus familis
XP_534932
2114
236979
S2107
S
E
E
E
L
Q
D
S
R
A
H
T
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q01815
2139
240120
Rat
Rattus norvegicus
P22002
2169
243464
S2162
S
E
E
A
L
P
D
S
R
S
Y
V
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
E2183
Y
E
E
D
L
A
D
E
M
I
C
I
T
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571975
2168
243196
E2160
N
S
P
L
M
E
D
E
D
M
E
C
V
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24270
2516
276682
R2507
V
Q
Q
Q
S
P
L
R
G
Q
G
N
Q
T
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94
90.9
N.A.
91.2
90.5
N.A.
N.A.
66.4
N.A.
76.5
N.A.
44.4
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
95.3
92.2
N.A.
92.9
92.4
N.A.
N.A.
76.6
N.A.
84.1
N.A.
57.2
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
73.3
N.A.
0
73.3
N.A.
N.A.
40
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
0
80
N.A.
N.A.
66.6
N.A.
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
0
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% C
% Asp:
0
0
0
13
0
0
75
0
13
0
0
0
0
0
0
% D
% Glu:
0
63
63
38
0
13
0
25
0
0
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
13
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
13
63
0
13
0
0
0
0
0
0
0
63
% L
% Met:
0
0
0
0
13
0
0
0
13
13
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% N
% Pro:
0
0
13
0
0
25
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
13
13
0
38
0
0
0
13
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
50
0
0
0
0
0
0
% R
% Ser:
50
13
0
0
13
0
0
50
0
13
0
0
38
50
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
13
13
25
0
% T
% Val:
13
0
0
0
0
0
0
0
0
25
0
38
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
38
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _