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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPS All Species: 11.82
Human Site: Y166 Identified Species: 21.67
UniProt: Q13938 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13938 NP_004049.1 189 20967 Y166 L A E F Q D Y Y S G V S A S M
Chimpanzee Pan troglodytes XP_001148406 198 23043 Y174 T P E E F M N Y Y A G V S A S
Rhesus Macaque Macaca mulatta XP_001093047 198 23099 Y174 T P E E F M N Y Y A G V S A S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q6P8Y1 208 24097 Y184 T P E E F M N Y Y A G V S A S
Rat Rattus norvegicus Q5U206 149 16784 Q127 E E V D E M I Q A A D T D G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513054 240 26670 Y217 A E E F L D Y Y S G V S T S V
Chicken Gallus gallus XP_423733 208 23903 Y184 T T E E F M N Y Y A G V S A S
Frog Xenopus laevis NP_001086262 198 22738 Y174 T G E E F L N Y Y S G V S A S
Zebra Danio Brachydanio rerio NP_001017776 199 23030 Y174 T K E E F M N Y Y S G V S A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731744 213 24154 N188 V T R E E F I N Y Y A T I S A
Honey Bee Apis mellifera XP_392882 222 25595 Y198 T E E E F M N Y Y S A I S A S
Nematode Worm Caenorhab. elegans O16305 149 16806 R127 E E V D E M I R E A D I D G D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZR02 154 17571 D132 M Q V D V D G D G R V N Y M E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.5 52 N.A. N.A. 51.4 28.5 N.A. 58.7 50 49.4 52.2 N.A. 42.2 39.6 28 N.A.
Protein Similarity: 100 74.7 74.7 N.A. N.A. 72.5 44.4 N.A. 70 72.1 69.1 74.3 N.A. 62.9 61.2 43.9 N.A.
P-Site Identity: 100 13.3 13.3 N.A. N.A. 13.3 0 N.A. 66.6 13.3 13.3 13.3 N.A. 6.6 13.3 0 N.A.
P-Site Similarity: 100 26.6 26.6 N.A. N.A. 26.6 20 N.A. 73.3 26.6 26.6 26.6 N.A. 26.6 26.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 8 47 16 0 8 54 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 24 0 24 0 8 0 0 16 0 16 0 16 % D
% Glu: 16 31 70 62 24 0 0 0 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 16 54 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 8 0 8 16 47 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 24 0 0 0 0 16 8 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 62 0 0 0 0 0 0 0 8 8 % M
% Asn: 0 0 0 0 0 0 54 8 0 0 0 8 0 0 0 % N
% Pro: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 16 24 0 16 54 24 54 % S
% Thr: 54 16 0 0 0 0 0 0 0 0 0 16 8 0 0 % T
% Val: 8 0 24 0 8 0 0 0 0 0 24 47 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 16 70 62 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _