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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
16.67
Human Site:
S506
Identified Species:
24.44
UniProt:
Q13948
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13948
NP_001904.2
678
77455
S506
D
S
L
L
S
I
I
S
S
Q
R
E
R
F
R
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
A733
R
E
M
E
A
Q
Q
A
A
L
D
P
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
A999
R
E
M
E
A
Q
Q
A
A
L
D
P
A
L
K
Dog
Lupus familis
XP_546939
1411
154543
R727
R
S
I
L
Q
Q
A
R
R
E
M
E
A
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70403
678
77250
S506
D
S
L
L
S
I
I
S
S
Q
R
E
R
F
R
Rat
Rattus norvegicus
P28023
1280
141912
A864
N
E
G
L
P
V
A
A
L
E
E
L
A
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
G1078
R
S
G
S
A
L
S
G
K
I
Y
A
S
T
Q
Chicken
Gallus gallus
P35458
1224
135524
S865
A
G
G
L
G
L
Q
S
Q
R
A
D
L
Q
R
Frog
Xenopus laevis
Q6PCJ1
1232
137267
K823
N
E
G
L
Q
A
L
K
L
E
D
V
A
F
K
Zebra Danio
Brachydanio rerio
NP_001003514
672
77022
S506
D
S
L
L
S
I
I
S
S
Q
R
E
R
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13496
1265
141199
T966
G
A
H
S
T
P
I
T
Q
R
A
Q
L
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8IA98
621
70934
R478
V
P
I
L
T
S
Q
R
N
R
L
H
E
R
V
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
K684
N
N
I
L
A
L
A
K
Q
E
M
E
A
Q
K
Poplar Tree
Populus trichocarpa
XP_002317937
689
79548
C508
S
S
M
L
K
V
I
C
N
Q
R
D
R
F
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LS42
689
79665
C515
S
S
M
L
K
V
I
C
S
Q
R
D
R
F
R
Baker's Yeast
Sacchar. cerevisiae
P34237
679
77495
T494
S
T
I
L
P
I
V
T
K
Q
R
D
R
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
31.4
35.9
N.A.
93.6
20.6
N.A.
20.7
20.5
20.9
72.4
N.A.
20.3
N.A.
27.7
27.8
Protein Similarity:
100
40.8
34.1
41.3
N.A.
96.6
33.5
N.A.
31.2
35
34.9
84.8
N.A.
36.2
N.A.
47.7
36.9
P-Site Identity:
100
0
0
20
N.A.
100
13.3
N.A.
6.6
20
13.3
100
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
33.3
33.3
40
N.A.
100
46.6
N.A.
26.6
40
40
100
N.A.
46.6
N.A.
33.3
60
Percent
Protein Identity:
31.6
N.A.
N.A.
31.7
25.1
N.A.
Protein Similarity:
56.6
N.A.
N.A.
55.4
47.5
N.A.
P-Site Identity:
53.3
N.A.
N.A.
60
46.6
N.A.
P-Site Similarity:
80
N.A.
N.A.
80
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
25
7
19
19
13
0
13
7
38
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
0
0
0
0
19
25
0
0
0
% D
% Glu:
0
25
0
13
0
0
0
0
0
25
7
32
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% F
% Gly:
7
7
25
0
7
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
25
0
0
25
38
0
0
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
13
0
0
13
13
0
0
0
0
0
38
% K
% Leu:
0
0
19
75
0
19
7
0
13
13
7
7
13
13
0
% L
% Met:
0
0
25
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
19
7
0
0
0
0
0
0
13
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
13
7
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
13
19
25
0
19
38
0
7
0
19
13
% Q
% Arg:
25
0
0
0
0
0
0
13
7
19
38
0
38
7
44
% R
% Ser:
19
44
0
13
19
7
7
25
25
0
0
0
7
0
0
% S
% Thr:
0
7
0
0
13
0
0
13
0
0
0
0
0
7
0
% T
% Val:
7
0
0
0
0
19
7
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _