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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 10
Human Site: S598 Identified Species: 14.67
UniProt: Q13948 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13948 NP_001904.2 678 77455 S598 Q R K Y L S L S P W D K A T L
Chimpanzee Pan troglodytes XP_527845 1515 165612 P1278 K R A Y Q Q K P Y P S P K T I
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 P1544 K R A Y Q Q K P Y P S P K T I
Dog Lupus familis XP_546939 1411 154543 A1193 K K P R V V L A P E E K E A L
Cat Felis silvestris
Mouse Mus musculus P70403 678 77250 S598 Q R K Y L G L S P W D K A T L
Rat Rattus norvegicus P28023 1280 141912 C1180 I T R S S P A C K S P S A Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 A1229 K K P R V V L A P E E K E A L
Chicken Gallus gallus P35458 1224 135524 G1109 N E N N R L K G A Q M K L E L
Frog Xenopus laevis Q6PCJ1 1232 137267 L1090 L H V P K L T L P K D R Q K E
Zebra Danio Brachydanio rerio NP_001003514 672 77022 S598 Q R R Y Q S L S P W D K A T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13496 1265 141199 I1172 P Q P Q D Q R I T A L E S E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8IA98 621 70934 M561 H D K T T L N M G R A I L A T
Sea Urchin Strong. purpuratus XP_780858 1460 163719 Y1394 R Q D N V K L Y E K I R F L Q
Poplar Tree Populus trichocarpa XP_002317937 689 79548 G624 D Q R Y K E L G F R D R I T L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS42 689 79665 G622 E Q R I K D L G I R D R I T L
Baker's Yeast Sacchar. cerevisiae P34237 679 77495 H586 F R Q N E L N H Y K N K K L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 31.4 35.9 N.A. 93.6 20.6 N.A. 20.7 20.5 20.9 72.4 N.A. 20.3 N.A. 27.7 27.8
Protein Similarity: 100 40.8 34.1 41.3 N.A. 96.6 33.5 N.A. 31.2 35 34.9 84.8 N.A. 36.2 N.A. 47.7 36.9
P-Site Identity: 100 20 20 26.6 N.A. 93.3 13.3 N.A. 26.6 13.3 13.3 86.6 N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 33.3 33.3 60 N.A. 93.3 20 N.A. 60 13.3 20 93.3 N.A. 26.6 N.A. 6.6 33.3
Percent
Protein Identity: 31.6 N.A. N.A. 31.7 25.1 N.A.
Protein Similarity: 56.6 N.A. N.A. 55.4 47.5 N.A.
P-Site Identity: 33.3 N.A. N.A. 26.6 13.3 N.A.
P-Site Similarity: 53.3 N.A. N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 7 13 7 7 7 0 25 19 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 0 7 7 0 0 0 0 38 0 0 0 0 % D
% Glu: 7 7 0 0 7 7 0 0 7 13 13 7 13 13 7 % E
% Phe: 7 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % F
% Gly: 0 0 0 0 0 7 0 19 7 0 0 0 0 0 0 % G
% His: 7 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 7 0 0 0 7 7 0 7 7 13 0 13 % I
% Lys: 25 13 19 0 19 7 19 0 7 19 0 44 19 7 0 % K
% Leu: 7 0 0 0 13 25 50 7 0 0 7 0 13 13 63 % L
% Met: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % M
% Asn: 7 0 7 19 0 0 13 0 0 0 7 0 0 0 0 % N
% Pro: 7 0 19 7 0 7 0 13 38 13 7 13 0 0 0 % P
% Gln: 19 25 7 7 19 19 0 0 0 7 0 0 7 7 7 % Q
% Arg: 7 38 25 13 7 0 7 0 0 19 0 25 0 0 0 % R
% Ser: 0 0 0 7 7 13 0 19 0 7 13 7 7 0 7 % S
% Thr: 0 7 0 7 7 0 7 0 7 0 0 0 0 44 7 % T
% Val: 0 0 7 0 19 13 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % W
% Tyr: 0 0 0 38 0 0 0 7 19 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _