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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
22.12
Human Site:
T227
Identified Species:
32.44
UniProt:
Q13948
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13948
NP_001904.2
678
77455
T227
T
E
L
F
D
L
K
T
K
Y
D
E
E
T
T
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
T227
T
E
L
F
D
L
K
T
K
Y
D
E
E
T
T
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
T493
T
E
L
F
D
L
K
T
K
Y
D
E
E
T
T
Dog
Lupus familis
XP_546939
1411
154543
T348
T
E
L
F
D
L
K
T
K
Y
D
E
E
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P70403
678
77250
T227
T
E
L
F
D
L
K
T
K
Y
D
E
E
T
T
Rat
Rattus norvegicus
P28023
1280
141912
N366
L
K
Q
L
E
E
Q
N
A
R
L
K
D
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
C262
T
E
L
L
D
L
R
C
K
Y
D
E
E
A
T
Chicken
Gallus gallus
P35458
1224
135524
Q379
D
L
S
A
S
E
K
Q
E
H
V
K
L
Q
K
Frog
Xenopus laevis
Q6PCJ1
1232
137267
Q344
D
L
S
A
S
E
K
Q
E
H
I
K
V
Q
K
Zebra Danio
Brachydanio rerio
NP_001003514
672
77022
T227
T
E
L
F
D
L
K
T
K
N
D
E
E
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13496
1265
141199
R430
S
E
V
T
E
L
E
R
T
K
E
K
L
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8IA98
621
70934
R216
S
K
N
K
D
I
Q
R
K
L
E
I
A
K
Q
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
A228
S
E
L
F
D
I
K
A
K
Y
D
E
Q
G
E
Poplar Tree
Populus trichocarpa
XP_002317937
689
79548
A238
S
Q
L
F
E
V
R
A
Q
S
E
E
E
W
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LS42
689
79665
A245
N
Q
L
F
E
L
R
A
Q
S
D
E
E
T
A
Baker's Yeast
Sacchar. cerevisiae
P34237
679
77495
G213
S
K
N
I
D
I
E
G
N
G
N
E
D
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
31.4
35.9
N.A.
93.6
20.6
N.A.
20.7
20.5
20.9
72.4
N.A.
20.3
N.A.
27.7
27.8
Protein Similarity:
100
40.8
34.1
41.3
N.A.
96.6
33.5
N.A.
31.2
35
34.9
84.8
N.A.
36.2
N.A.
47.7
36.9
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
73.3
6.6
6.6
86.6
N.A.
13.3
N.A.
13.3
60
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
80
26.6
26.6
93.3
N.A.
60
N.A.
46.6
80
Percent
Protein Identity:
31.6
N.A.
N.A.
31.7
25.1
N.A.
Protein Similarity:
56.6
N.A.
N.A.
55.4
47.5
N.A.
P-Site Identity:
26.6
N.A.
N.A.
46.6
13.3
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
19
7
0
0
0
7
13
19
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
63
0
0
0
0
0
57
0
13
0
7
% D
% Glu:
0
57
0
0
25
19
13
0
13
0
19
69
57
0
7
% E
% Phe:
0
0
0
57
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
7
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
19
0
0
0
0
7
7
0
7
0
% I
% Lys:
0
19
0
7
0
0
57
0
57
7
0
25
0
7
13
% K
% Leu:
7
13
63
13
0
57
0
0
0
7
7
0
13
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
13
0
0
0
0
7
7
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
7
0
0
0
13
13
13
0
0
0
7
13
7
% Q
% Arg:
0
0
0
0
0
0
19
13
0
7
0
0
0
0
0
% R
% Ser:
32
0
13
0
13
0
0
0
0
13
0
0
0
13
0
% S
% Thr:
44
0
0
7
0
0
0
38
7
0
0
0
0
32
44
% T
% Val:
0
0
7
0
0
7
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
44
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _