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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 27.27
Human Site: T325 Identified Species: 40
UniProt: Q13948 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13948 NP_001904.2 678 77455 T325 Q R L Q A S L T K L R E N S A
Chimpanzee Pan troglodytes XP_527845 1515 165612 T325 Q R L Q A S L T K L R E N S A
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 T591 Q R L Q A S L T K L R E N S A
Dog Lupus familis XP_546939 1411 154543 T446 Q R L Q A S L T K L R E N S A
Cat Felis silvestris
Mouse Mus musculus P70403 678 77250 T325 Q R L Q A S L T K L R E N S A
Rat Rattus norvegicus P28023 1280 141912 R485 R E T E L E L R E Q L D M A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 Q362 Q H L Q N S L Q E L E E S S A
Chicken Gallus gallus P35458 1224 135524 R479 R E T E L E L R E Q L D L A A
Frog Xenopus laevis Q6PCJ1 1232 137267 R444 R E T E L E L R E Q L D M A G
Zebra Danio Brachydanio rerio NP_001003514 672 77022 S325 Q R L Q A S L S A L R E N T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13496 1265 141199 S641 I L V I L L I S R I V F K C D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8IA98 621 70934 V308 K R H E A S H V E E L A K W K
Sea Urchin Strong. purpuratus XP_780858 1460 163719 N326 Q R L Q A S S N K L R D S T A
Poplar Tree Populus trichocarpa XP_002317937 689 79548 T326 H N I E T T L T N E R E Q H I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS42 689 79665 A333 H N V E T A L A N E R E S H V
Baker's Yeast Sacchar. cerevisiae P34237 679 77495 S305 E Q E R K S T S H A I N E L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 31.4 35.9 N.A. 93.6 20.6 N.A. 20.7 20.5 20.9 72.4 N.A. 20.3 N.A. 27.7 27.8
Protein Similarity: 100 40.8 34.1 41.3 N.A. 96.6 33.5 N.A. 31.2 35 34.9 84.8 N.A. 36.2 N.A. 47.7 36.9
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 60 13.3 6.6 73.3 N.A. 0 N.A. 20 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. 73.3 46.6 40 86.6 N.A. 33.3 N.A. 40 86.6
Percent
Protein Identity: 31.6 N.A. N.A. 31.7 25.1 N.A.
Protein Similarity: 56.6 N.A. N.A. 55.4 47.5 N.A.
P-Site Identity: 26.6 N.A. N.A. 20 6.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 50 7 0 7 7 7 0 7 0 19 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 7 % D
% Glu: 7 19 7 38 0 19 0 0 32 19 7 57 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % G
% His: 13 7 7 0 0 0 7 0 7 0 0 0 0 13 7 % H
% Ile: 7 0 7 7 0 0 7 0 0 7 7 0 0 0 7 % I
% Lys: 7 0 0 0 7 0 0 0 38 0 0 0 13 0 13 % K
% Leu: 0 7 50 0 25 7 75 0 0 50 25 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 13 0 0 7 0 0 7 13 0 0 7 38 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 50 7 0 50 0 0 0 7 0 19 0 0 7 0 0 % Q
% Arg: 19 50 0 7 0 0 0 19 7 0 57 0 0 0 0 % R
% Ser: 0 0 0 0 0 63 7 19 0 0 0 0 19 38 0 % S
% Thr: 0 0 19 0 13 7 7 38 0 0 0 0 0 13 0 % T
% Val: 0 0 13 0 0 0 0 7 0 0 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _