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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
6.67
Human Site:
T434
Identified Species:
9.78
UniProt:
Q13948
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13948
NP_001904.2
678
77455
T434
R
I
T
E
A
V
A
T
A
T
E
Q
R
E
L
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
P434
D
Q
P
E
S
R
R
P
G
S
L
P
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
P700
D
Q
P
E
S
R
R
P
G
S
L
P
A
P
P
Dog
Lupus familis
XP_546939
1411
154543
Q555
S
S
Q
S
P
L
Q
Q
S
P
D
V
N
G
M
Cat
Felis silvestris
Mouse
Mus musculus
P70403
678
77250
K434
H
L
T
E
A
T
A
K
A
V
E
Q
K
E
L
Rat
Rattus norvegicus
P28023
1280
141912
Q771
G
R
L
R
A
F
L
Q
G
G
Q
E
A
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
S727
H
A
A
N
G
T
G
S
S
T
S
E
D
A
I
Chicken
Gallus gallus
P35458
1224
135524
Q765
C
R
L
R
A
F
L
Q
A
G
Q
E
A
S
D
Frog
Xenopus laevis
Q6PCJ1
1232
137267
F610
A
V
G
E
Q
M
S
F
A
A
G
L
V
Y
S
Zebra Danio
Brachydanio rerio
NP_001003514
672
77022
T434
E
F
S
T
A
V
Q
T
T
S
D
Q
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13496
1265
141199
T806
I
I
Q
E
A
G
A
T
S
D
S
V
L
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8IA98
621
70934
E416
R
N
E
E
Q
E
A
E
L
T
V
L
K
E
K
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
F447
G
L
A
Q
A
Q
A
F
A
S
L
I
G
Q
E
Poplar Tree
Populus trichocarpa
XP_002317937
689
79548
K443
K
I
T
E
L
T
A
K
V
N
E
Q
Q
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LS42
689
79665
K450
K
G
E
E
L
T
A
K
V
N
E
Q
Q
R
L
Baker's Yeast
Sacchar. cerevisiae
P34237
679
77495
Q420
S
V
D
Q
L
K
Q
Q
I
A
T
L
K
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
31.4
35.9
N.A.
93.6
20.6
N.A.
20.7
20.5
20.9
72.4
N.A.
20.3
N.A.
27.7
27.8
Protein Similarity:
100
40.8
34.1
41.3
N.A.
96.6
33.5
N.A.
31.2
35
34.9
84.8
N.A.
36.2
N.A.
47.7
36.9
P-Site Identity:
100
6.6
6.6
0
N.A.
60
6.6
N.A.
6.6
13.3
13.3
40
N.A.
33.3
N.A.
33.3
20
P-Site Similarity:
100
20
20
26.6
N.A.
73.3
20
N.A.
33.3
26.6
33.3
66.6
N.A.
46.6
N.A.
40
46.6
Percent
Protein Identity:
31.6
N.A.
N.A.
31.7
25.1
N.A.
Protein Similarity:
56.6
N.A.
N.A.
55.4
47.5
N.A.
P-Site Identity:
46.6
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
13
0
44
0
44
0
32
13
0
0
25
7
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
7
0
0
0
0
0
0
7
13
0
7
0
13
% D
% Glu:
7
0
13
57
0
7
0
7
0
0
25
19
0
32
7
% E
% Phe:
0
7
0
0
0
13
0
13
0
0
0
0
0
0
0
% F
% Gly:
13
7
7
0
7
7
7
0
19
13
7
0
7
7
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
19
0
0
0
0
0
0
7
0
0
7
0
0
13
% I
% Lys:
13
0
0
0
0
7
0
19
0
0
0
0
25
7
7
% K
% Leu:
0
13
13
0
19
7
13
0
7
0
19
19
7
7
32
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
7
0
0
0
0
0
13
0
0
7
0
0
% N
% Pro:
0
0
13
0
7
0
0
13
0
7
0
13
0
13
13
% P
% Gln:
0
13
13
13
13
7
19
25
0
0
13
32
13
7
0
% Q
% Arg:
13
13
0
13
0
13
13
0
0
0
0
0
7
7
0
% R
% Ser:
13
7
7
7
13
0
7
7
19
25
13
0
0
7
7
% S
% Thr:
0
0
19
7
0
25
0
19
7
19
7
0
0
7
0
% T
% Val:
0
13
0
0
0
13
0
0
13
7
7
13
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _