Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 31.21
Human Site: T56 Identified Species: 45.78
UniProt: Q13948 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13948 NP_001904.2 678 77455 T56 S R E F K K N T P E D L R K Q
Chimpanzee Pan troglodytes XP_527845 1515 165612 T56 S R E F K K N T P E D L R K Q
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 T322 S R E F K K N T P E D L R K Q
Dog Lupus familis XP_546939 1411 154543 T193 S R E F K K N T P E I D A L S
Cat Felis silvestris
Mouse Mus musculus P70403 678 77250 T56 S R E F K K N T P E D L R K Q
Rat Rattus norvegicus P28023 1280 141912 K135 T S K L R G L K P K K A P T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 V91 R R E F K K N V P E E I R E M
Chicken Gallus gallus P35458 1224 135524 E222 S Q V R D L E E K L E T L K I
Frog Xenopus laevis Q6PCJ1 1232 137267 E187 A Q V K D L E E K L E T L K M
Zebra Danio Brachydanio rerio NP_001003514 672 77022 T56 S R E F K K N T P E D L R K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13496 1265 141199 E252 T L K Q R R N E D K E R L R E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8IA98 621 70934 L63 S R K V A I P L I K A F Q S E
Sea Urchin Strong. purpuratus XP_780858 1460 163719 T57 S R E F K K N T P E D V R K Q
Poplar Tree Populus trichocarpa XP_002317937 689 79548 S70 T R D F K K A S S D E K L G L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS42 689 79665 S77 T R D F K K A S P E N K L S M
Baker's Yeast Sacchar. cerevisiae P34237 679 77495 E57 T K K F K K L E P E E K L N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 31.4 35.9 N.A. 93.6 20.6 N.A. 20.7 20.5 20.9 72.4 N.A. 20.3 N.A. 27.7 27.8
Protein Similarity: 100 40.8 34.1 41.3 N.A. 96.6 33.5 N.A. 31.2 35 34.9 84.8 N.A. 36.2 N.A. 47.7 36.9
P-Site Identity: 100 100 100 66.6 N.A. 100 6.6 N.A. 60 13.3 6.6 93.3 N.A. 6.6 N.A. 13.3 93.3
P-Site Similarity: 100 100 100 66.6 N.A. 100 33.3 N.A. 80 26.6 26.6 93.3 N.A. 60 N.A. 40 100
Percent
Protein Identity: 31.6 N.A. N.A. 31.7 25.1 N.A.
Protein Similarity: 56.6 N.A. N.A. 55.4 47.5 N.A.
P-Site Identity: 26.6 N.A. N.A. 40 33.3 N.A.
P-Site Similarity: 60 N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 13 0 0 0 7 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 13 0 0 0 7 7 38 7 0 0 0 % D
% Glu: 0 0 50 0 0 0 13 25 0 63 38 0 0 7 13 % E
% Phe: 0 0 0 69 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 7 7 0 0 7 % I
% Lys: 0 7 25 7 69 69 0 7 13 19 7 19 0 50 0 % K
% Leu: 0 7 0 7 0 13 13 7 0 13 0 32 38 7 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % M
% Asn: 0 0 0 0 0 0 57 0 0 0 7 0 0 7 7 % N
% Pro: 0 0 0 0 0 0 7 0 69 0 0 0 7 0 0 % P
% Gln: 0 13 0 7 0 0 0 0 0 0 0 0 7 0 32 % Q
% Arg: 7 69 0 7 13 7 0 0 0 0 0 7 44 7 0 % R
% Ser: 57 7 0 0 0 0 0 13 7 0 0 0 0 13 7 % S
% Thr: 32 0 0 0 0 0 0 44 0 0 0 13 0 7 0 % T
% Val: 0 0 13 7 0 0 0 7 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _