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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 13.03
Human Site: Y557 Identified Species: 19.11
UniProt: Q13948 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13948 NP_001904.2 678 77455 Y557 K I K F L Q S Y P G R G S G S
Chimpanzee Pan troglodytes XP_527845 1515 165612 P1237 D S Q P C E P P S V G T E Y S
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 P1503 D S Q P C E P P S V G T E Y S
Dog Lupus familis XP_546939 1411 154543 K1152 M E K K A Y M K R R H S S V S
Cat Felis silvestris
Mouse Mus musculus P70403 678 77250 Y557 K I K F L Q S Y P G R G I G S
Rat Rattus norvegicus P28023 1280 141912 E1139 K F S L P P H E G P G G N L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 Y1188 K A Y L K R R Y G L I S T G S
Chicken Gallus gallus P35458 1224 135524 G1068 Q Q R G V G A G Q A A G G S A
Frog Xenopus laevis Q6PCJ1 1232 137267 Q1049 K D S P L L L Q Q I D A L R L
Zebra Danio Brachydanio rerio NP_001003514 672 77022 Y557 K I K F L Q S Y P T R A G D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13496 1265 141199 E1131 P V V A E E V E L L K N A F N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8IA98 621 70934 I520 N I R L C E R I R F L Q S P G
Sea Urchin Strong. purpuratus XP_780858 1460 163719 S1353 S L L P I V S S Q R E R F R I
Poplar Tree Populus trichocarpa XP_002317937 689 79548 E583 R G S K K H A E D L E S G F A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS42 689 79665 E581 R G S K K Y V E D L E S G F S
Baker's Yeast Sacchar. cerevisiae P34237 679 77495 Y545 R I R Y L Q S Y N N N N A P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 31.4 35.9 N.A. 93.6 20.6 N.A. 20.7 20.5 20.9 72.4 N.A. 20.3 N.A. 27.7 27.8
Protein Similarity: 100 40.8 34.1 41.3 N.A. 96.6 33.5 N.A. 31.2 35 34.9 84.8 N.A. 36.2 N.A. 47.7 36.9
P-Site Identity: 100 6.6 6.6 20 N.A. 93.3 13.3 N.A. 26.6 6.6 13.3 73.3 N.A. 0 N.A. 13.3 6.6
P-Site Similarity: 100 20 20 20 N.A. 93.3 20 N.A. 40 40 13.3 73.3 N.A. 33.3 N.A. 26.6 20
Percent
Protein Identity: 31.6 N.A. N.A. 31.7 25.1 N.A.
Protein Similarity: 56.6 N.A. N.A. 55.4 47.5 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 13 0 0 7 7 13 13 0 13 % A
% Cys: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 7 0 0 0 0 0 0 13 0 7 0 0 7 0 % D
% Glu: 0 7 0 0 7 25 0 25 0 0 19 0 13 0 0 % E
% Phe: 0 7 0 19 0 0 0 0 0 7 0 0 7 19 0 % F
% Gly: 0 13 0 7 0 7 0 7 13 13 19 25 25 19 7 % G
% His: 0 0 0 0 0 7 7 0 0 0 7 0 0 0 0 % H
% Ile: 0 32 0 0 7 0 0 7 0 7 7 0 7 0 7 % I
% Lys: 38 0 25 19 19 0 0 7 0 0 7 0 0 0 0 % K
% Leu: 0 7 7 19 32 7 7 0 7 25 7 0 7 7 13 % L
% Met: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 7 7 7 13 7 0 7 % N
% Pro: 7 0 0 25 7 7 13 13 19 7 0 0 0 13 0 % P
% Gln: 7 7 13 0 0 25 0 7 19 0 0 7 0 0 0 % Q
% Arg: 19 0 19 0 0 7 13 0 13 13 19 7 0 13 0 % R
% Ser: 7 13 25 0 0 0 32 7 13 0 0 25 19 7 50 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 13 7 0 0 % T
% Val: 0 7 7 0 7 7 13 0 0 13 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 13 0 32 0 0 0 0 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _