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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 15.76
Human Site: Y575 Identified Species: 23.11
UniProt: Q13948 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13948 NP_001904.2 678 77455 Y575 E L R Y S S Q Y E E R L D P F
Chimpanzee Pan troglodytes XP_527845 1515 165612 L1255 S P Q P Q H Q L K K P R V V L
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 L1521 S P Q P Q H Q L K K P R V V L
Dog Lupus familis XP_546939 1411 154543 G1170 P C E P P S V G I D Y S Q G A
Cat Felis silvestris
Mouse Mus musculus P70403 678 77250 Y575 E L R Y S S Q Y E E R L D P F
Rat Rattus norvegicus P28023 1280 141912 L1157 L Y R K T S Q L L E K L N Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 C1206 S P S T R S E C A S P S L Q P
Chicken Gallus gallus P35458 1224 135524 L1086 Q V K D S P L L L Q Q I E A L
Frog Xenopus laevis Q6PCJ1 1232 137267 K1067 H L K H E N N K L K A H Q I K
Zebra Danio Brachydanio rerio NP_001003514 672 77022 Y575 V M R Y S S Q Y E E R L D P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13496 1265 141199 A1149 N Q R L R L Q A Q D M R A K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8IA98 621 70934 L538 Q A N V E A G L G N D F R N G
Sea Urchin Strong. purpuratus XP_780858 1460 163719 Q1371 E L E G E S R Q H Q Q Q N I I
Poplar Tree Populus trichocarpa XP_002317937 689 79548 Y601 E S K Y K K I Y E D D I N P F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LS42 689 79665 Y599 E S K Y K K I Y E D D I N P F
Baker's Yeast Sacchar. cerevisiae P34237 679 77495 S563 T E R I D V E S Q Y S R V Y D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.3 31.4 35.9 N.A. 93.6 20.6 N.A. 20.7 20.5 20.9 72.4 N.A. 20.3 N.A. 27.7 27.8
Protein Similarity: 100 40.8 34.1 41.3 N.A. 96.6 33.5 N.A. 31.2 35 34.9 84.8 N.A. 36.2 N.A. 47.7 36.9
P-Site Identity: 100 6.6 6.6 6.6 N.A. 100 33.3 N.A. 6.6 6.6 6.6 86.6 N.A. 13.3 N.A. 0 20
P-Site Similarity: 100 26.6 26.6 13.3 N.A. 100 53.3 N.A. 13.3 53.3 33.3 93.3 N.A. 26.6 N.A. 13.3 46.6
Percent
Protein Identity: 31.6 N.A. N.A. 31.7 25.1 N.A.
Protein Similarity: 56.6 N.A. N.A. 55.4 47.5 N.A.
P-Site Identity: 40 N.A. N.A. 40 6.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 7 0 7 7 0 7 0 7 7 7 % A
% Cys: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 7 0 0 0 0 25 19 0 19 0 7 % D
% Glu: 32 7 13 0 19 0 13 0 32 25 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 32 % F
% Gly: 0 0 0 7 0 0 7 7 7 0 0 0 0 7 7 % G
% His: 7 0 0 7 0 13 0 0 7 0 0 7 0 0 0 % H
% Ile: 0 0 0 7 0 0 13 0 7 0 0 19 0 13 7 % I
% Lys: 0 0 25 7 13 13 0 7 13 19 7 0 0 7 7 % K
% Leu: 7 25 0 7 0 7 7 32 19 0 0 25 7 0 32 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 7 0 7 0 0 7 7 0 0 7 0 0 25 7 0 % N
% Pro: 7 19 0 19 7 7 0 0 0 0 19 0 0 32 7 % P
% Gln: 13 7 13 0 13 0 44 7 13 13 13 7 13 13 0 % Q
% Arg: 0 0 38 0 13 0 7 0 0 0 19 25 7 0 0 % R
% Ser: 19 13 7 0 25 44 0 7 0 7 7 13 0 0 0 % S
% Thr: 7 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 7 0 7 0 7 7 0 0 0 0 0 19 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 32 0 0 0 32 0 7 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _