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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6H
All Species:
13.13
Human Site:
S2
Identified Species:
32.1
UniProt:
Q13956
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13956
NP_006196.1
83
9074
S2
_
_
_
_
_
_
M
S
D
N
T
T
L
P
A
Chimpanzee
Pan troglodytes
XP_001158553
83
9000
S2
_
_
_
_
_
_
M
S
D
N
A
T
L
A
A
Rhesus Macaque
Macaca mulatta
XP_001091111
83
9000
S2
_
_
_
_
_
_
M
S
D
N
T
A
L
A
A
Dog
Lupus familis
XP_853743
83
9056
S2
_
_
_
_
_
_
M
S
D
N
T
T
L
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P09174
87
9619
P6
_
_
M
N
L
E
P
P
K
G
E
I
R
S
A
Rat
Rattus norvegicus
P61250
83
9026
S2
_
_
_
_
_
_
M
S
D
S
P
C
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512154
88
9675
P7
_
M
S
L
E
P
P
P
R
A
E
P
K
S
A
Chicken
Gallus gallus
NP_989739
85
9259
N4
_
_
_
_
M
S
E
N
P
T
T
N
L
T
T
Frog
Xenopus laevis
NP_001086232
87
9267
P6
_
_
M
N
G
N
S
P
A
S
S
A
L
A
P
Zebra Danio
Brachydanio rerio
NP_997964
87
9605
P6
_
_
M
N
L
E
P
P
K
P
E
I
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
97.5
97.5
N.A.
75.8
91.5
N.A.
77.2
88.2
79.3
74.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
97.5
97.5
N.A.
83.9
93.9
N.A.
85.2
90.5
86.2
83.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
77.7
77.7
77.7
N.A.
7.6
44.4
N.A.
7.1
18.1
7.6
7.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
77.7
77.7
77.7
N.A.
7.6
55.5
N.A.
7.1
27.2
30.7
7.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
10
20
0
40
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
20
10
0
0
0
30
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
0
0
20
0
0
% K
% Leu:
0
0
0
10
20
0
0
0
0
0
0
0
70
0
0
% L
% Met:
0
10
30
0
10
0
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
30
0
10
0
10
0
40
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
30
40
10
10
10
10
0
10
30
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
0
10
0
0
10
10
50
0
20
10
0
0
40
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
40
30
0
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
100
90
60
60
50
50
0
0
0
0
0
0
0
0
0
% _