Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDE6H All Species: 34.55
Human Site: T18 Identified Species: 84.44
UniProt: Q13956 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13956 NP_006196.1 83 9074 T18 A S N Q G P T T P R K G P P K
Chimpanzee Pan troglodytes XP_001158553 83 9000 T18 A S N Q G P T T P R K G P P K
Rhesus Macaque Macaca mulatta XP_001091111 83 9000 T18 A S N Q G P T T P R K G P P K
Dog Lupus familis XP_853743 83 9056 T18 A S N Q G P T T P R K G P P K
Cat Felis silvestris
Mouse Mus musculus P09174 87 9619 T22 R V I G G P V T P R K G P P K
Rat Rattus norvegicus P61250 83 9026 T18 A P S Q G P T T P R K G P P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512154 88 9675 T23 R V T G G P V T P R K G P P K
Chicken Gallus gallus NP_989739 85 9259 T20 D A P T G P T T P R K G P P K
Frog Xenopus laevis NP_001086232 87 9267 T22 N N S G G P T T P R K G P P K
Zebra Danio Brachydanio rerio NP_997964 87 9605 T22 R V T G G P A T P R K G P P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 97.5 97.5 N.A. 75.8 91.5 N.A. 77.2 88.2 79.3 74.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 97.5 97.5 N.A. 83.9 93.9 N.A. 85.2 90.5 86.2 83.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 66.6 86.6 N.A. 66.6 73.3 73.3 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 66.6 93.3 N.A. 66.6 80 86.6 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 40 100 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 100 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 40 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 0 100 0 0 100 0 0 0 100 100 0 % P
% Gln: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 30 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 40 20 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 20 10 0 0 70 100 0 0 0 0 0 0 0 % T
% Val: 0 30 0 0 0 0 20 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _