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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
24.55
Human Site:
S1097
Identified Species:
60
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
S1097
D
I
S
N
L
I
A
S
E
I
I
R
N
E
D
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
S1095
D
I
S
N
L
I
A
S
E
I
I
R
N
E
D
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
I346
N
H
Q
Y
S
L
Q
I
L
A
H
C
K
Q
N
Dog
Lupus familis
XP_545892
1304
148017
S1077
D
I
S
N
L
I
A
S
E
I
I
R
N
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
S1084
H
V
S
N
F
I
A
S
E
I
I
R
N
E
D
Rat
Rattus norvegicus
P28818
1244
142649
S1066
H
I
S
N
L
I
A
S
E
I
L
R
N
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
S1073
I
M
N
Y
A
D
V
S
S
R
A
N
S
I
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
S1066
D
M
S
N
L
V
A
S
Q
I
M
S
H
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
S522
K
V
I
A
V
S
S
S
S
E
T
L
T
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
R1040
N
I
L
A
V
T
R
R
F
N
E
V
S
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
100
0
100
N.A.
80
80
N.A.
6.6
N.A.
N.A.
53.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
86.6
93.3
N.A.
33.3
N.A.
N.A.
86.6
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
10
0
60
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
40
0
0
0
0
10
0
0
0
0
0
0
0
10
50
% D
% Glu:
0
0
0
0
0
0
0
0
50
10
10
0
0
50
20
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
10
50
10
0
0
50
0
10
0
60
40
0
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
0
0
10
0
50
10
0
0
10
0
10
10
0
0
10
% L
% Met:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
20
0
10
60
0
0
0
0
0
10
0
10
50
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
10
0
50
0
0
0
% R
% Ser:
0
0
60
0
10
10
10
80
20
0
0
10
20
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
10
10
0
% T
% Val:
0
20
0
0
20
10
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _