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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
4.24
Human Site:
S539
Identified Species:
10.37
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
S539
T
E
E
E
A
K
G
S
G
Q
D
I
D
H
L
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
S539
T
E
E
E
A
K
G
S
G
Q
D
T
D
H
L
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
Dog
Lupus familis
XP_545892
1304
148017
Q539
T
E
E
D
G
S
S
Q
D
I
D
H
L
D
F
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
A543
L
D
D
E
A
K
G
A
G
P
E
I
E
H
L
Rat
Rattus norvegicus
P28818
1244
142649
N531
T
L
L
D
D
P
E
N
M
D
D
D
G
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
D538
C
I
L
I
E
E
P
D
A
S
D
D
D
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
D530
C
T
L
I
E
E
P
D
A
N
D
E
D
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
L500
C
F
L
F
T
K
H
L
L
I
T
S
R
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
93.3
0
26.6
N.A.
53.3
13.3
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
93.3
0
33.3
N.A.
86.6
26.6
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
30
0
0
10
20
0
0
0
0
10
0
% A
% Cys:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
20
10
0
0
20
10
10
60
20
40
10
0
% D
% Glu:
0
30
30
30
20
20
10
0
0
0
10
10
10
0
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
0
30
0
30
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
10
0
30
0
% H
% Ile:
0
10
0
20
0
0
0
0
0
20
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
40
0
0
0
0
0
0
0
10
20
% K
% Leu:
10
10
40
0
0
0
0
10
10
0
0
0
10
10
30
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
20
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
10
10
20
0
10
0
10
0
0
10
% S
% Thr:
40
10
0
0
10
0
0
0
0
0
10
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _