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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRF1 All Species: 0.61
Human Site: S835 Identified Species: 1.48
UniProt: Q13972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13972 NP_722522.1 1275 145383 S835 P S A L S K Q S S E V S M R E
Chimpanzee Pan troglodytes XP_001153586 1273 145146 E835 A L S K Q S S E V S M R E E S
Rhesus Macaque Macaca mulatta XP_001108408 514 59608 S100 H Y F T V N F S H E N Q K A L
Dog Lupus familis XP_545892 1304 148017 Q828 R E E S D N D Q T Q S D D G D
Cat Felis silvestris
Mouse Mus musculus P27671 1262 144083 H836 E S E D D Q N H S D E D N T E
Rat Rattus norvegicus P28818 1244 142649 D820 D I L K E E S D D D Q S D V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510010 1242 141041 I827 C N K L R R S I R R A V L E S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEA7 1244 141569 D818 N A E V P R I D A L C G K L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122143 690 76494 D276 M D N V H F N D L L R G S L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780300 1211 137984 I791 M S H S A P N I A A L V K A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 39.6 93.3 N.A. 83.4 83.1 N.A. 64.8 N.A. N.A. 65.3 N.A. N.A. 25.1 N.A. 48
Protein Similarity: 100 99.4 39.9 94.9 N.A. 90.3 90.3 N.A. 78.7 N.A. N.A. 78.4 N.A. N.A. 36.3 N.A. 65.5
P-Site Identity: 100 0 13.3 0 N.A. 20 6.6 N.A. 6.6 N.A. N.A. 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 13.3 13.3 20 N.A. 33.3 26.6 N.A. 26.6 N.A. N.A. 26.6 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 10 0 0 0 20 10 10 0 0 20 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 10 10 0 10 20 0 10 30 10 20 0 20 20 0 20 % D
% Glu: 10 10 30 0 10 10 0 10 0 20 10 0 10 20 20 % E
% Phe: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 20 0 10 0 % G
% His: 10 0 10 0 10 0 0 10 10 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 20 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 20 0 10 0 0 0 0 0 0 30 0 0 % K
% Leu: 0 10 10 20 0 0 0 0 10 20 10 0 10 20 10 % L
% Met: 20 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % M
% Asn: 10 10 10 0 0 20 30 0 0 0 10 0 10 0 0 % N
% Pro: 10 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 10 10 10 0 10 10 10 0 0 0 % Q
% Arg: 10 0 0 0 10 20 0 0 10 10 10 10 0 10 10 % R
% Ser: 0 30 10 20 10 10 30 20 20 10 10 20 10 0 30 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % T
% Val: 0 0 0 20 10 0 0 0 10 0 10 20 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _