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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRF1 All Species: 2.42
Human Site: S839 Identified Species: 5.93
UniProt: Q13972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13972 NP_722522.1 1275 145383 S839 S K Q S S E V S M R E E S D I
Chimpanzee Pan troglodytes XP_001153586 1273 145146 R839 Q S S E V S M R E E S D I D Q
Rhesus Macaque Macaca mulatta XP_001108408 514 59608 Q104 V N F S H E N Q K A L E L R T
Dog Lupus familis XP_545892 1304 148017 D832 D N D Q T Q S D D G D T E A S
Cat Felis silvestris
Mouse Mus musculus P27671 1262 144083 D840 D Q N H S D E D N T E V S P V
Rat Rattus norvegicus P28818 1244 142649 S824 E E S D D D Q S D V D D T E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510010 1242 141041 V831 R R S I R R A V L E S A S L D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEA7 1244 141569 G822 P R I D A L C G K L R R S I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122143 690 76494 G280 H F N D L L R G S L S D T S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780300 1211 137984 V795 A P N I A A L V K A A K P D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 39.6 93.3 N.A. 83.4 83.1 N.A. 64.8 N.A. N.A. 65.3 N.A. N.A. 25.1 N.A. 48
Protein Similarity: 100 99.4 39.9 94.9 N.A. 90.3 90.3 N.A. 78.7 N.A. N.A. 78.4 N.A. N.A. 36.3 N.A. 65.5
P-Site Identity: 100 6.6 20 0 N.A. 20 6.6 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 20 20 N.A. 40 53.3 N.A. 20 N.A. N.A. 20 N.A. N.A. 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 20 10 10 0 0 20 10 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 10 30 10 20 0 20 20 0 20 30 0 30 10 % D
% Glu: 10 10 0 10 0 20 10 0 10 20 20 20 10 10 0 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 20 0 10 0 0 0 0 0 % G
% His: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 20 0 0 0 0 0 0 0 0 10 10 10 % I
% Lys: 0 10 0 0 0 0 0 0 30 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 10 20 10 0 10 20 10 0 10 10 0 % L
% Met: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 20 30 0 0 0 10 0 10 0 0 0 0 0 0 % N
% Pro: 10 10 0 0 0 0 0 0 0 0 0 0 10 10 10 % P
% Gln: 10 10 10 10 0 10 10 10 0 0 0 0 0 0 10 % Q
% Arg: 10 20 0 0 10 10 10 10 0 10 10 10 0 10 10 % R
% Ser: 10 10 30 20 20 10 10 20 10 0 30 0 40 10 20 % S
% Thr: 0 0 0 0 10 0 0 0 0 10 0 10 20 0 10 % T
% Val: 10 0 0 0 10 0 10 20 0 10 0 10 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _