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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
5.15
Human Site:
S844
Identified Species:
12.59
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
S844
E
V
S
M
R
E
E
S
D
I
D
Q
N
Q
S
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
I844
S
M
R
E
E
S
D
I
D
Q
N
Q
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
L109
E
N
Q
K
A
L
E
L
R
T
E
D
A
K
D
Dog
Lupus familis
XP_545892
1304
148017
E837
Q
S
D
D
G
D
T
E
A
S
P
T
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
S845
D
E
D
N
T
E
V
S
P
V
K
S
P
P
T
Rat
Rattus norvegicus
P28818
1244
142649
T829
D
Q
S
D
V
D
D
T
E
V
S
P
P
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
S836
R
A
V
L
E
S
A
S
L
D
R
P
I
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
S827
L
C
G
K
L
R
R
S
I
R
R
A
V
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
T285
L
R
G
S
L
S
D
T
S
S
V
T
M
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
P800
A
L
V
K
A
A
K
P
D
P
I
P
I
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
13.3
13.3
0
N.A.
13.3
6.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
40
26.6
13.3
N.A.
33.3
46.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
20
10
10
0
10
0
0
10
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
20
20
0
20
30
0
30
10
10
10
0
10
20
% D
% Glu:
20
10
0
10
20
20
20
10
10
0
10
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
10
10
0
20
0
0
% I
% Lys:
0
0
0
30
0
0
10
0
0
0
10
0
10
10
0
% K
% Leu:
20
10
0
10
20
10
0
10
10
0
0
0
0
10
0
% L
% Met:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
10
10
30
20
40
30
% P
% Gln:
10
10
10
0
0
0
0
0
0
10
0
20
0
10
10
% Q
% Arg:
10
10
10
0
10
10
10
0
10
10
20
0
0
0
0
% R
% Ser:
10
10
20
10
0
30
0
40
10
20
10
10
10
10
10
% S
% Thr:
0
0
0
0
10
0
10
20
0
10
0
20
0
10
10
% T
% Val:
0
10
20
0
10
0
10
0
0
20
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _