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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRF1 All Species: 2.73
Human Site: S875 Identified Species: 6.67
UniProt: Q13972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13972 NP_722522.1 1275 145383 S875 K S V K N K N S S E F P L F S
Chimpanzee Pan troglodytes XP_001153586 1273 145146 E875 V K S K N S S E F P L F S Y N
Rhesus Macaque Macaca mulatta XP_001108408 514 59608 M140 A T E H E A L M Q K Y L H L L
Dog Lupus familis XP_545892 1304 148017 V868 F S Y N N G V V M T S C R E L
Cat Felis silvestris
Mouse Mus musculus P27671 1262 144083 T876 Y N N G I L M T T C R D L V D
Rat Rattus norvegicus P28818 1244 142649 C860 N S G I M M T C R D L M D S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510010 1242 141041 Y867 S T P R H L R Y R Q P G Q A A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEA7 1244 141569 R858 P G E I S P C R S P S T P R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122143 690 76494 C316 F S R T L N S C K V P Q I R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780300 1211 137984 V831 S S P P N T T V S A G V V V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 39.6 93.3 N.A. 83.4 83.1 N.A. 64.8 N.A. N.A. 65.3 N.A. N.A. 25.1 N.A. 48
Protein Similarity: 100 99.4 39.9 94.9 N.A. 90.3 90.3 N.A. 78.7 N.A. N.A. 78.4 N.A. N.A. 36.3 N.A. 65.5
P-Site Identity: 100 13.3 0 13.3 N.A. 6.6 6.6 N.A. 0 N.A. N.A. 6.6 N.A. N.A. 13.3 N.A. 20
P-Site Similarity: 100 33.3 20 13.3 N.A. 26.6 20 N.A. 33.3 N.A. N.A. 13.3 N.A. N.A. 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 10 0 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 10 20 0 10 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 10 % D
% Glu: 0 0 20 0 10 0 0 10 0 10 0 0 0 10 0 % E
% Phe: 20 0 0 0 0 0 0 0 10 0 10 10 0 10 0 % F
% Gly: 0 10 10 10 0 10 0 0 0 0 10 10 0 0 0 % G
% His: 0 0 0 10 10 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 20 10 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 10 10 0 20 0 10 0 0 10 10 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 20 10 0 0 0 20 10 20 10 20 % L
% Met: 0 0 0 0 10 10 10 10 10 0 0 10 0 0 0 % M
% Asn: 10 10 10 10 40 10 10 0 0 0 0 0 0 0 20 % N
% Pro: 10 0 20 10 0 10 0 0 0 20 20 10 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 10 0 10 10 0 0 % Q
% Arg: 0 0 10 10 0 0 10 10 20 0 10 0 10 20 0 % R
% Ser: 20 50 10 0 10 10 20 10 30 0 20 0 10 10 20 % S
% Thr: 0 20 0 10 0 10 20 10 10 10 0 10 0 0 10 % T
% Val: 10 0 10 0 0 0 10 20 0 10 0 10 10 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 0 10 0 0 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _