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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
8.79
Human Site:
T193
Identified Species:
21.48
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
T193
E
R
I
Q
S
T
Q
T
V
A
P
N
D
E
D
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
T193
E
R
I
Q
S
T
Q
T
V
A
P
N
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
Dog
Lupus familis
XP_545892
1304
148017
T193
E
R
I
Q
S
T
Q
T
V
T
P
N
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
A197
R
I
Q
S
S
N
K
A
G
S
A
D
D
E
D
Rat
Rattus norvegicus
P28818
1244
142649
L193
E
R
I
Q
S
N
Q
L
V
A
P
E
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
Q200
K
E
R
M
R
P
Y
Q
G
N
Q
E
D
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
H192
K
E
R
M
R
P
Y
H
V
F
Q
E
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
A169
Q
E
L
T
A
E
V
A
K
L
K
T
E
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
100
0
93.3
N.A.
26.6
80
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
46.6
80
N.A.
26.6
N.A.
N.A.
33.3
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
20
0
30
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
60
0
70
% D
% Glu:
40
30
0
0
0
10
0
0
0
0
0
30
20
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
40
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
10
0
10
0
0
0
10
0
% L
% Met:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
0
0
10
0
30
0
0
10
% N
% Pro:
0
0
0
0
0
20
0
0
0
0
40
0
0
0
0
% P
% Gln:
10
0
10
40
0
0
40
10
0
0
20
0
0
0
0
% Q
% Arg:
10
40
20
0
20
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
50
0
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
30
0
30
0
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _