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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF1
All Species:
28.18
Human Site:
T399
Identified Species:
68.89
UniProt:
Q13972
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13972
NP_722522.1
1275
145383
T399
L
H
D
V
L
A
H
T
P
H
E
H
V
E
R
Chimpanzee
Pan troglodytes
XP_001153586
1273
145146
T399
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
Dog
Lupus familis
XP_545892
1304
148017
T399
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P27671
1262
144083
T403
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Rat
Rattus norvegicus
P28818
1244
142649
T399
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
T406
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
T398
L
H
E
L
L
A
H
T
P
H
E
H
V
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
T363
M
L
L
K
Q
Y
E
T
K
P
V
C
E
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
39.6
93.3
N.A.
83.4
83.1
N.A.
64.8
N.A.
N.A.
65.3
N.A.
N.A.
25.1
N.A.
48
Protein Similarity:
100
99.4
39.9
94.9
N.A.
90.3
90.3
N.A.
78.7
N.A.
N.A.
78.4
N.A.
N.A.
36.3
N.A.
65.5
P-Site Identity:
100
86.6
0
86.6
N.A.
86.6
86.6
N.A.
86.6
N.A.
N.A.
86.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
60
0
0
0
10
0
0
0
70
0
10
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
70
0
0
70
0
70
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
70
10
10
60
70
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
70
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _