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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRF1 All Species: 20.3
Human Site: Y1249 Identified Species: 49.63
UniProt: Q13972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13972 NP_722522.1 1275 145383 Y1249 H Q A K V T Q Y L L D Q S F V
Chimpanzee Pan troglodytes XP_001153586 1273 145146 Y1247 H Q A K V T Q Y L L D Q S F V
Rhesus Macaque Macaca mulatta XP_001108408 514 59608 E489 L S L K K E G E R Q C F L F F
Dog Lupus familis XP_545892 1304 148017 Q1229 H Q V K V S R Q C S D P W A L
Cat Felis silvestris
Mouse Mus musculus P27671 1262 144083 Y1236 P Q P K V I Q Y L L D E S F M
Rat Rattus norvegicus P28818 1244 142649 Y1218 P Q P K V T Q Y L V D E T F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510010 1242 141041 Y1216 H Q A K V T Q Y L L D K T L I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEA7 1244 141569 Y1218 H Q P K V T Q Y L L D K T L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122143 690 76494 Q665 Q E I E M S S Q Q G N F Q H D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780300 1211 137984 R1184 A H V V R E I R H F Q H T N Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 39.6 93.3 N.A. 83.4 83.1 N.A. 64.8 N.A. N.A. 65.3 N.A. N.A. 25.1 N.A. 48
Protein Similarity: 100 99.4 39.9 94.9 N.A. 90.3 90.3 N.A. 78.7 N.A. N.A. 78.4 N.A. N.A. 36.3 N.A. 65.5
P-Site Identity: 100 100 13.3 33.3 N.A. 66.6 66.6 N.A. 73.3 N.A. N.A. 66.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 13.3 53.3 N.A. 80 86.6 N.A. 93.3 N.A. N.A. 86.6 N.A. N.A. 33.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 30 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 10 % D
% Glu: 0 10 0 10 0 20 0 10 0 0 0 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 20 0 50 10 % F
% Gly: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % G
% His: 50 10 0 0 0 0 0 0 10 0 0 10 0 10 0 % H
% Ile: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 80 10 0 0 0 0 0 0 20 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 60 50 0 0 10 20 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % N
% Pro: 20 0 30 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 10 70 0 0 0 0 60 20 10 10 10 20 10 0 0 % Q
% Arg: 0 0 0 0 10 0 10 10 10 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 20 10 0 0 10 0 0 30 0 0 % S
% Thr: 0 0 0 0 0 50 0 0 0 0 0 0 40 0 0 % T
% Val: 0 0 20 10 70 0 0 0 0 10 0 0 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _